The emergence of chimera states in a network of nephrons

被引:4
作者
Khouhak, Jalal [1 ]
Faghani, Zahra [1 ]
Laugesen, Jakob L. [2 ]
Jafari, Sajad [1 ]
机构
[1] Amirkabir Univ Technol, Biomed Engn Dept, Tehran 158754413, Iran
[2] Univ Copenhagen, Dept Food Sci, Copenhagen, Denmark
关键词
Chimera state; Multi-stability; Kidney; Nephron model; TUBULOGLOMERULAR FEEDBACK; PRESSURE OSCILLATIONS; DYNAMICS; SYNCHRONIZATION;
D O I
10.1016/j.cjph.2019.10.024
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
The kidney plays an essential role in our body, mainly by controlling secretion and reabsorption of water and salts. The kidneys consist of a large number of nephrons which are the functional units of the kidney. The interactions between these nephrons induce different behaviors which can be considered by a dynamical model. In this paper, a network of coupled nephron models and its dynamics is investigated. Numerical simulations of the network reveal various types of dynamical patterns depending on the coupling function and strength. One of the observed phenomenon is the emergence of chimera state. A chimera state is defined by the coexistence of coherent and incoherent groups in a network of identical oscillators. The occurrence of the chimera state can be related to the situation of disturbed synchronous oscillation of the TGF-mediated proximal pressure.
引用
收藏
页码:402 / 409
页数:8
相关论文
共 37 条
[1]   Chimera states for coupled oscillators [J].
Abrams, DM ;
Strogatz, SH .
PHYSICAL REVIEW LETTERS, 2004, 93 (17) :174102-1
[2]   Bifurcation analysis of nephron pressure and flow regulation [J].
Barfred, M ;
Mosekilde, E ;
HolsteinRathlou, NH .
CHAOS, 1996, 6 (03) :280-287
[3]   Chimera states: Effects of different coupling topologies [J].
Bera, Bidesh K. ;
Majhi, Soumen ;
Ghosh, Dibakar ;
Perc, Matjaz .
EPL, 2017, 118 (01)
[4]   Imperfect traveling chimera states induced by local synaptic gradient coupling [J].
Bera, Bidesh K. ;
Ghosh, Dibakar ;
Banerjee, Tanmoy .
PHYSICAL REVIEW E, 2016, 94 (01)
[5]   Chimera states in purely local delay-coupled oscillators [J].
Bera, Bidesh K. ;
Ghosh, Dibakar .
PHYSICAL REVIEW E, 2016, 93 (05)
[6]   Chimera states in bursting neurons [J].
Bera, Bidesh K. ;
Ghosh, Dibakar ;
Lakshmanan, M. .
PHYSICAL REVIEW E, 2016, 93 (01)
[7]   Effects of different initial conditions on the emergence of chimera states [J].
Faghani, Zahra ;
Arab, Zahra ;
Parastesh, Fatemeh ;
Jafari, Sajad ;
Perc, Matjaz ;
Slavinec, Mitja .
CHAOS SOLITONS & FRACTALS, 2018, 114 :306-311
[8]   ANALYSIS OF INTERACTION BETWEEN TGF AND THE MYOGENIC RESPONSE IN RENAL BLOOD-FLOW AUTOREGULATION [J].
FELDBERG, R ;
COLDINGJORGENSEN, M ;
HOLSTEINRATHLOU, NH .
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL FLUID AND ELECTROLYTE PHYSIOLOGY, 1995, 269 (04) :F581-F593
[9]   Chimera states in population dynamics: Networks with fragmented and hierarchical connectivities [J].
Hizanidis, Johanne ;
Panagakou, Evangelia ;
Omelchenko, Iryna ;
Schoell, Eckehard ;
Hoevel, Philipp ;
Provata, Astero .
PHYSICAL REVIEW E, 2015, 92 (01)
[10]   Synchronization phenomena in nephron-nephron interaction [J].
Holstein-Rathlou, NH ;
Yip, KP ;
Sosnovtseva, OV ;
Mosekilde, E .
CHAOS, 2001, 11 (02) :417-426