Role of TRP Channels in the Regulation of the Endosomal Pathway

被引：55
作者：
Abe, Ken [1 ]
Puertollano, Rosa [1 ]
机构：
[1] NHLBI, Cell Biol Lab, NIH, Bethesda, MD 20892 USA
来源：
PHYSIOLOGY | 2011年 / 26卷 / 01期
关键词：
MUCOLIPIDOSIS TYPE-IV; RECEPTOR POTENTIAL CHANNEL; ADENINE-DINUCLEOTIDE PHOSPHATE; VARITINT-WADDLER PHENOTYPE; CYCLIC ADP-RIBOSE; PLASMA-MEMBRANE; CATION CHANNEL; CA2+-PERMEABLE CHANNEL; ENDOCYTIC PATHWAY; CELL DEGENERATION;
D O I：
10.1152/physiol.00048.2010
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
Some members of the transient receptor potential (TRP) channel superfamily have proved to be essential in maintaining adequate ion homeostasis, signaling, and membrane trafficking in the endosomal pathway. The unique properties of the TRP channels confer cells the ability to integrate cytosolic and intraluminal stimuli and allow maintained and regulated release of Ca2+ from endosomes and lysosomes.
引用
收藏
页码：14 / 22
页数：9
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