Role of TRP Channels in the Regulation of the Endosomal Pathway

被引:55
作者
Abe, Ken [1 ]
Puertollano, Rosa [1 ]
机构
[1] NHLBI, Cell Biol Lab, NIH, Bethesda, MD 20892 USA
关键词
MUCOLIPIDOSIS TYPE-IV; RECEPTOR POTENTIAL CHANNEL; ADENINE-DINUCLEOTIDE PHOSPHATE; VARITINT-WADDLER PHENOTYPE; CYCLIC ADP-RIBOSE; PLASMA-MEMBRANE; CATION CHANNEL; CA2+-PERMEABLE CHANNEL; ENDOCYTIC PATHWAY; CELL DEGENERATION;
D O I
10.1152/physiol.00048.2010
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Some members of the transient receptor potential (TRP) channel superfamily have proved to be essential in maintaining adequate ion homeostasis, signaling, and membrane trafficking in the endosomal pathway. The unique properties of the TRP channels confer cells the ability to integrate cytosolic and intraluminal stimuli and allow maintained and regulated release of Ca2+ from endosomes and lysosomes.
引用
收藏
页码:14 / 22
页数:9
相关论文
共 101 条
[1]   The neurogenetics of mucolipidosis type IV [J].
Altarescu, G ;
Sun, M ;
Moore, DF ;
Smith, JA ;
Wiggs, EA ;
Solomon, BI ;
Patronas, NJ ;
Frei, KP ;
Gupta, S ;
Kaneski, CR ;
Quarrell, OW ;
Slaugenhaupt, SA ;
Goldin, E ;
Schiffmann, R .
NEUROLOGY, 2002, 59 (03) :306-313
[2]  
AMIR N, 1987, PEDIATRICS, V79, P953
[3]   Insulin/phosphoinositide 3-kinase pathway accelerates the glucose-induced first-phase insulin secretion through TrpV2 recruitment in pancreatic β-cells [J].
Aoyagi, Kyota ;
Ohara-Imaizumi, Mica ;
Nishiwaki, Chiyono ;
Nakamichi, Yoko ;
Nagamatsu, Shinya .
BIOCHEMICAL JOURNAL, 2010, 432 :375-386
[4]   Mucolipidosis type IV [J].
Bach, G .
MOLECULAR GENETICS AND METABOLISM, 2001, 73 (03) :197-203
[5]   Identification of the gene causing mucolipidosis type IV [J].
Bargal, R ;
Avidan, N ;
Ben-Asher, E ;
Olender, Z ;
Zeigler, M ;
Frumkin, A ;
Raas-Rothschild, A ;
Glusman, G ;
Lancet, D ;
Bach, G .
NATURE GENETICS, 2000, 26 (01) :118-121
[6]   Cloning of the gene encoding a novel integral membrane protein, mucolipidin - and identification of the two major founder mutations causing mucolipidosis type IV [J].
Bassi, MT ;
Manzoni, M ;
Monti, E ;
Pizzo, MT ;
Ballabio, A ;
Borsani, G .
AMERICAN JOURNAL OF HUMAN GENETICS, 2000, 67 (05) :1110-1120
[7]   Nicotinic acid adenine dinucleotide phosphate and cyclic ADP-ribose regulate TRPM2 channels in T lymphocytes [J].
Beck, Andreas ;
Kolisek, Martin ;
Bagley, Leigh Anne ;
Fleig, Andrea ;
Penner, Reinhold .
FASEB JOURNAL, 2006, 20 (07) :962-+
[8]  
Beech DJ, 2004, J PHYSIOL-LONDON, V559, P685, DOI 10.1113/jphysiol.2004.068734
[9]   Differential gene expression of TPLPM1, the potential cause of congenital stationary night blindness and coat spotting patterns (LP) in the appaloosa horse (Equus caballus) [J].
Bellone, Rebecca R. ;
Brooks, Samantha A. ;
Sandmeyer, Lynne ;
Murphy, Barbara A. ;
Forsyth, George ;
Archer, Sheila ;
Bailey, Ernest ;
Grahn, Bruce .
GENETICS, 2008, 179 (04) :1861-1870
[10]   CONGENITAL CORNEAL CLOUDING WITH ABNORMAL SYSTEMIC STORAGE BODIES - NEW VARIANT OF MUCOLIPIDOSIS [J].
BERMAN, ER ;
LIVNI, N ;
SHAPIRA, E ;
MERIN, S ;
LEVIJ, IS .
JOURNAL OF PEDIATRICS, 1974, 84 (04) :519-526