Sulfamic acid as a novel, efficient, cost-effective, and reusable solid acid catalyst for the synthesis of pyrroles under solvent-free conditions

被引：19
|
作者：
De, Surya K. [1 ]
机构：
[1] Burnham Inst Med Res, La Jolla, CA 92037 USA
来源：
SYNTHETIC COMMUNICATIONS | 2008年 / 38卷 / 05期
关键词：
Paal-Knorr reaction; pyrroles; solvent-free conditions; sulfamic acid;
D O I：
10.1080/00397910701821051
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Paal-Knorr condensation of 2,5-hexadione with primary amines in the presence of a catalytic amount of sulfamic acid under solvent-free conditions has been accomplished with an excellent yield. This is a very easy, rapid, and high-yielding reaction for the synthesis N-substituted pyrrole derivatives.
引用
收藏
页码：803 / 809
页数：7
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