New intramolecular cyclization and rearrangement processes based on the radical aryl-aryl coupling of arylsubstituted 2-azetidinones

被引：34
作者：
Alcaide, B [1 ]
Rodríguez-Vicente, A [1 ]
机构：
[1] Univ Complutense, Fac Quim, Dept Quim Organ 1, E-28040 Madrid, Spain
来源：
TETRAHEDRON LETTERS | 1998年 / 39卷 / 36期
关键词：
D O I：
10.1016/S0040-4039(98)01373-2
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
New polycyclic 2-azetidinones having fused or not biaryl units are easily prepared by the tin-mediated, intramolecular aryl-aryl radical cyclization of readily available arylsubstituted 2-azetidinones. The regioselectivity and efficiency of the process is determined both by the length of the linking chain through the beta-lactam nucleus and by the number and position of the substituents on the aromatic acceptor ring. (C) 1998 Elsevier Science Ltd. All rights reserved.
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页码：6589 / 6592
页数：4
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