Allocation of scarce biospecimens for use in research

被引：1

作者：

Pierson, Leah ^{[1
]}

Gibert, Sophia ^{[2
]}

Berkman, Benjamin ^{[3
]}

Danis, Marion ^{[3
]}

Millum, Joseph ^{[4
]}

机构：

[1] Harvard Med Sch, MD PhD Program, Boston, MA 02115 USA

[2] MIT, PhD Program Philosophy, 77 Massachusetts Ave, Cambridge, MA 02139 USA

[3] NIH, Dept Bioeth, Bldg 10, Bethesda, MD 20892 USA

[4] NIH, Clin Ctr, Dept Bioeth, Fogarty Int Ctr, Bldg 10, Bethesda, MD 20892 USA

来源：

JOURNAL OF MEDICAL ETHICS | 2021年 / 47卷 / 11期

关键词：

allocation of health care resources; donation; procurement of organs; tissues; ethics; research ethics; resource allocation; HEALTH RESEARCH;

D O I：

10.1136/medethics-2019-105766

中图分类号：

B82 [伦理学（道德学）];

学科分类号：

摘要：

Hundreds of millions of rare biospecimens are stored in laboratories and biobanks around the world. Often, the researchers who possess these specimens do not plan to use them, while other researchers limit the scope of their work because they cannot acquire biospecimens that meet their needs. This situation raises an important and underexplored question: how should scientists allocate biospecimens that they do not intend to use? We argue that allocators should aim to maximise the social value of the research enterprise when allocating scarce biospecimens. We provide an ethical framework for assessing the social value of proposed research projects and describe how the framework could be implemented.

引用

页码：740 / 743

页数：4

共 13 条

[1] The Social Value of Health Research and the Worst Off [J].

Barsdorf, Nicola ;

Millum, Joseph .

BIOETHICS, 2017, 31 (02) :105-115

[2]

Daniels N., 2004, How to achieve fair distribution of ARTs in '3 by 5': fair process and legitimacy in patient selection

[3] Human tissue models for a human disease: what are the barriers? [J].

Edwards, Joanna ;

Belvisi, Maria ;

Dahlen, Sven-Erik ;

Holgate, Stephen ;

Holmes, Anthony .

THORAX, 2015, 70 (07) :695-697

[4]

[Eiseman Elisa Case Studies of Existing Human Tissue Repositories Case Studies of Existing Human Tissue Repositories], [No title captured]

[5] What makes clinical research ethical? [J].

Emanuel, EJ ;

Wendler, D ;

Grady, C .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2000, 283 (20) :2701-2711

[6] Access policies in biobank research: what criteria do they include and how publicly available are they? A cross-sectional study [J].

Langhof, Holger ;

Kahrass, Hannes ;

Sievers, Soeren ;

Strech, Daniel .

EUROPEAN JOURNAL OF HUMAN GENETICS, 2017, 25 (03) :293-300

[7] International Charter of principles for sharing bio-specimens and data [J].

Mascalzoni, Deborah ;

Dove, Edward S. ;

Rubinstein, Yaffa ;

Dawkins, Hugh J. S. ;

Kole, Anna ;

McCormack, Pauline ;

Woods, Simon ;

Riess, Olaf ;

Schaefer, Franz ;

Lochmueller, Hanns ;

Knoppers, Bartha M. ;

Hansson, Mats .

EUROPEAN JOURNAL OF HUMAN GENETICS, 2015, 23 (06) :721-728

[8]

Massett Holly A., 2011, Journal of the National Cancer Institute Monographs, P8, DOI 10.1093/jncimonographs/lgr007

[9] Biobanking from the patient perspective [J].

Mitchell D. ;

Geissler J. ;

Parry-Jones A. ;

Keulen H. ;

Schmitt D.C. ;

Vavassori R. ;

Matharoo-Ball B. .

Research Involvement and Engagement, 1 (1)

[10] Motivations and Barriers to Sharing Biological Samples: A Case Study [J].

Pereira, Stacey .

JOURNAL OF PERSONALIZED MEDICINE, 2013, 3 (02) :102-110

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