The prognostic value of additional malignant lesions detected by magnetic resonance imaging versus mammography

被引：3

作者：

Saha, Sukamal ^{[1
]}

Freyvogel, Mary ^{[2
]}

Johnston, Gregory ^{[2
]}

Lawrence, Linda ^{[1
]}

Conlin, Chris ^{[1
]}

Hicks, Randy ^{[3
]}

Strahle, David ^{[3
]}

Korant, Alpesh ^{[1
]}

Shaik, Mohammed ^{[4
]}

Wiese, David ^{[1
]}

机构：

[1] McLaren Flint, Flint, MI 48532 USA

[2] McLaren Macomb, Mt Clemens, MI USA

[3] Reg Med Imaging, Flint, MI USA

[4] Hurley Reg Med Ctr, Flint, MI USA

来源：

AMERICAN JOURNAL OF SURGERY | 2015年 / 209卷 / 02期

关键词：

MRI and breast cancer; Nodal positivity and MRI; MULTICENTRIC BREAST-CANCER; MRI; CARCINOMA;

D O I：

10.1016/j.amjsurg.2014.05.004

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

BACKGROUND: Nodal positivity is correlated with a poorer prognosis in breast cancer. A study was composed to compare nodal positivity in patients with single versus multiple lesions found on magnetic resonance imaging (MRI) and mammogram (MMG). METHODS: A retrospective study of breast cancer patients undergoing MRI and MMG was performed. Nodal positivity was compared in patients with additional invasive lesions found on MRI versus single invasive lesions found on MRI and MMG. RESULTS: A total of 425 patients were included. The overall nodal positivity was 23.8%. Patients with single versus multiple malignant lesions had nodal positivity of 20.9% vs 31.1% (P = .04). MRI detected multiple lesions in 120 patients, 80 of which were not detected by MMG (18.8%). Comparing single lesions with additional malignant lesions detected by MRI only, nodal positivity increased from 20.9% to 51.6% (P = .0002). CONCLUSIONS: Patients with additional invasive lesions on MRI had significantly higher nodal positivity than single invasive lesions. Hence, addition of MRI in early-stage breast cancer may have prognostic value because of detection of potential node-positive patients. (C) 2015 Elsevier Inc. All rights reserved.

引用

页码：398 / 402

页数：5

共 9 条

[1] Pathologic analysis of tumor size and lymph node status in multifocal/multicentric breast carcinoma [J].