Rapid synthesis of hollow nano-structured hydroxyapatite rnicrospheres via microwave transformation method using hollow CaCO3 precursor microspheres

被引：30

作者：

Chen, Hongguang ^{[1
]}

Leng, Senlin ^{[2
]}

机构：

[1] Shanghai Nanotechnol Promot Ctr, Shanghai 200237, Peoples R China

[2] Tongren Univ, Inst Phys & Elect Engn, Tongren 554300, Peoples R China

来源：

CERAMICS INTERNATIONAL | 2015年 / 41卷 / 02期

关键词：

Hydroxyapatite; Hollow microspheres; Microwave; Ultrafast synthesis; Hard-template transformation; DRUG-DELIVERY; HYDROTHERMAL SYNTHESIS; PROTEIN ADSORPTION; OSTEOGENIC DIFFERENTIATION; AQUEOUS-SOLUTION; SURFACTANT-FREE; NANOPARTICLES; NANOPOWDERS; NANOWIRES; PHOSPHATE;

D O I：

10.1016/j.ceramint.2014.10.021

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Hollow nano-structured hydroxyapatite [Ca-10(PO4)(6)(OH)(2), HAp] microspheres were rapidly synthesized via microwave transformation of a sacrificial hard-template of similarly structured calcium carbonate (CaCO3) hollow microspheres in Na3PO4 aqueous solution. Results showed that the microwave process significantly increased transformation efficiency. Pure hollow HAp microspheres could be obtained within ultra-shortperiod of 30 min via the microwave transformation process, in comparison to over 48 h in the traditional hydrothermal transformation method. These studies suggest that the microwave assisted hard-template transformation process is an effective approach to synthesize HAp with high efficiency. The resulting hollow nano-structured HAp microspheres may have applications in drug-delivery and serve as materials for chemical and environmental applications. (C) 2014 Elsevier Ltd and Techna Group S.r.l. All rights reserved.

引用

页码：2209 / 2213

页数：5

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