Hypothalamic Neurons Take Center Stage in the Neural Stem Cell Niche

被引:29
作者
Andreotti, Julia P. [1 ]
Lousado, Luiza [1 ]
Magno, Luiz Alexandre V. [1 ]
Birbrair, Alexander [1 ,2 ,3 ]
机构
[1] Univ Fed Minas Gerais, Dept Pathol, Belo Horizonte, MG, Brazil
[2] Albert Einstein Coll Med, Dept Cell Biol, Bronx, NY 10467 USA
[3] Albert Einstein Coll Med, Ruth L & David S Gottesman Inst Stem Cell & Regen, Bronx, NY 10467 USA
关键词
POMC-EXPRESSING PROGENITORS; NEUROGENESIS;
D O I
10.1016/j.stem.2017.08.005
中图分类号
Q813 [细胞工程];
学科分类号
摘要
Neural stem cells (NSCs) are a heterogeneous population of cells that generate new neurons in adult animals. Recently in Science, Paul et al. (2017) show that hypothalamic neurons control activation of a subset of NSCs in response to feeding, providing insights into how physiological cues may influence stem cell activation.
引用
收藏
页码:293 / 294
页数:2
相关论文
共 10 条
[1]   Niche heterogeneity in the bone marrow [J].
Birbrair, Alexander ;
Frenette, Paul S. .
HEMATOPOIETIC STEM CELLS IX, 2016, 1370 :82-96
[2]   Sex differences and reproductive hormone influences on human odor perception [J].
Doty, Richard L. ;
Cameron, E. Leslie .
PHYSIOLOGY & BEHAVIOR, 2009, 97 (02) :213-228
[3]   The endomorphin system and its evolving neurophysiological role [J].
Fichna, Jakub ;
Janecka, Anna ;
Costentin, Jean ;
Do Rego, Jean-Claude .
PHARMACOLOGICAL REVIEWS, 2007, 59 (01) :88-123
[4]   μ- and κ-opioids induce the differentiation of embryonic stem cells to neural progenitors [J].
Kim, Eunhae ;
Clark, Amy L. ;
Kiss, Alexi ;
Hahn, Jason W. ;
Wesselschmidt, Robin ;
Coscia, Carmine J. ;
Belcheva, Mariana M. .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (44) :33749-33760
[5]   The Adult Ventricular-Subventricular Zone (V-SVZ) and Olfactory Bulb (OB) Neurogenesis [J].
Lim, Daniel A. ;
Alvarez-Buylla, Arturo .
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY, 2016, 8 (05)
[6]   Dentate gyrus NMDA receptors mediate rapid pattern separation in the hippocampal network [J].
McHugh, Thomas J. ;
Jones, Matthew W. ;
Quinn, Jennifer J. ;
Balthasar, Nina ;
Coppari, Roberto ;
Elmquist, Joel K. ;
Lowell, Bradford B. ;
Fanselow, Michael S. ;
Wilson, Matthew A. ;
Tonegawa, Susumu .
SCIENCE, 2007, 317 (5834) :94-99
[7]   Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions [J].
Ming, Guo-li ;
Song, Hongjun .
NEURON, 2011, 70 (04) :687-702
[8]   Pomc-expressing progenitors give rise to antagonistic neuronal populations in hypothalamic feeding circuits [J].
Padilla, Stephanie L. ;
Carmody, Jill S. ;
Zeltser, Lori M. .
NATURE MEDICINE, 2010, 16 (04) :403-405
[9]   Hypothalamic regulation of regionally distinct adult neural stem cells and neurogenesis [J].
Paul, Alex ;
Chaker, Zayna ;
Doetsch, Fiona .
SCIENCE, 2017, 356 (6345) :1383-1385
[10]   Fertility-Regulating Kiss1 Neurons Arise from Hypothalamic Pomc-Expressing Progenitors [J].
Sanz, Elisenda ;
Quintana, Albert ;
Deem, Jennifer D. ;
Steiner, Robert A. ;
Palmiter, Richard D. ;
McKnight, G. Stanley .
JOURNAL OF NEUROSCIENCE, 2015, 35 (14) :5549-5556