Applause sign helps to discriminate PSP from FTD and PD

被引:71
作者
Dubois, B
Slachevsky, A
Pillon, B
Beato, R
Villalponda, JM
Litvan, I
机构
[1] Hop La Pitie Salpetriere, INSERM, U610, F-75013 Paris, France
[2] Hop La Pitie Salpetriere, Federat Neurol, F-75013 Paris, France
[3] Hosp Salvador, Dept Neurol, Dementia & Cognit Neurol Unit, Santiago, Chile
[4] Univ Louisville, Movement Disorder Program, Louisville, KY 40292 USA
关键词
D O I
10.1212/01.WNL.0000165977.38272.15
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The "applause sign" is a simple test of motor control that helps to differentiate PSP from frontal or striatofrontal degenerative diseases. It was found in 0/39 controls, 0 of 24 patients with frontotemporal dementia (FTD), 0 of 17 patients with Parkinson disease ( PD), and 30/42 patients with progressive supranuclear palsy (PSP). It discriminated PSP from FTD (p < 0.001) and PD (p < 0.00). The "three clap test" correctly identified 81.8% of the patients in the comparison PSP and FTD and 75% of the patients in the comparison of PSP and PD.
引用
收藏
页码:2132 / 2133
页数:2
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