Radiotherapy for head and neck squamous cell carcinoma: State of the art and future directions

被引：6
作者：
Schick, U. [1 ]
Huguet, F. [2 ,3 ]
Pointreau, Y. [4 ]
Pradier, O. [1 ]
机构：
[1] CHRU Morvan, Inst Cancerol & Hematol, Serv Radiotherapie, 2 Ave Foch, F-29200 Brest, France
[2] Hop Tenon, Serv Oncol Radiotherapie, 4 Rue Chine, F-75020 Paris, France
[3] Univ Paris 06, 4 Rue Chine, F-75020 Paris, France
[4] Ctr Jean Bernard, Inst Interreg Cancerol, Serv Oncol Radiotherapie, Clin Victor Hugo, 9 Rue Beauverger, F-72000 Le Mans, France
来源：
CANCER RADIOTHERAPIE | 2017年 / 21卷 / 6-7期
关键词：
Radiotherapy; Head and neck; State of the art; LOCALLY ADVANCED HEAD; INTENSITY-MODULATED RADIOTHERAPY; STAGE NASOPHARYNGEAL CARCINOMA; ADAPTIVE RADIOTHERAPY; HUMAN-PAPILLOMAVIRUS; RANDOMIZED-TRIAL; STEREOTACTIC REIRRADIATION; ACCELERATED FRACTIONATION; CONCOMITANT CHEMOTHERAPY; RADIATION-THERAPY;
D O I：
10.1016/j.canrad.2017.07.032
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Therapeutic principles of radiation therapy in head and neck carcinomas will be discussed in this review. Intensity-modulated radiotherapy with concomitant cisplatin should be standard. In case of contraindication to chemotherapy, cetuximab is an option, while hyperfractionation should be considered in patients unfit for concomitant treatment. Concomitant chemotherapy should be administered in the presence of extracapsular extensions and positive margins in the postoperative setting. Current research areas such as desescalation in human papillomavirus-positive tumours, adaptive radiotherapy, radiomics and immunotherapy will also be addressed. (C) 2017 Societe francaise de radiotherapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：498 / 504
页数：7
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