Capillary electrophoretic separation of clomiphene isomers using various cyclodextrins as additives

被引：0

作者：

Juvancz, Z ^{[1
]}

Urmos, I ^{[1
]}

Klebovich, I ^{[1
]}

机构：

[1] EGIS PHARMACEUT,DEPT PHARMACOKINET,H-1106 BUDAPEST,HUNGARY

来源：

JOURNAL OF CAPILLARY ELECTROPHORESIS | 1996年 / 3卷 / 04期

关键词：

separation of cis-trans isomers; cyclodextrin additives; migration reversal; role of organic modifier;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The cis (Z) and trans (E) isomers of clomiphene were separated using capillary electrophoresis. Various derivatives of cyclodextrins (CDs) were applied as buffer additives, achieving a resolution of greater than 18. The effect of various parameters, type and concentration of CDs, type and concentration of background electrolytes (BGEs), pH, and organic modifiers has been studied systematically. Migration reversal was observed in several cases. The loadability of the various buffer systems was also taken into account.

引用

页码：181 / 189

页数：9

共 50 条

[1] Capillary electrophoretic separation and quantitation of ractopamine stereoisomers using cyclodextrins as chiral additives
Inoue, T
Chang, JP
JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, 2003, 26 (11) : 1677 - 1693
[2] The effect of β-cyclodextrins as buffer additives on the (capillary) electrophoretic separation of peptides and proteins
Zhang, R
Zhang, HX
Eaker, D
Hjerten, S
JOURNAL OF CAPILLARY ELECTROPHORESIS, 1997, 4 (03) : 105 - 112
[3] Capillary electrophoretic separation of α-, β-, γ- and δ-cyclodextrins using a dual electrolyte system
Larsen, KL
Zimmermann, W
JOURNAL OF CHROMATOGRAPHY A, 1998, 811 (1-2) : 193 - 199
[4] Capillary electrophoretic separation of α-, β-, γ- and δ-cyclodextrins using a dual electrolyte system
J Chromatogr, 1-2 (193-199):
[5] Enantiomer separation of disopyramide with capillary electrophoresis using various cyclodextrins
Juvancz, Z
Markides, KE
Jicsinszky, L
ELECTROPHORESIS, 1997, 18 (06) : 1002 - 1006
[6] CAPILLARY ELECTROPHORETIC SEPARATIONS OF PEPTIDES USING MICELLE-FORMING COMPOUNDS AND CYCLODEXTRINS AS ADDITIVES
LIU, JP
COBB, KA
NOVOTNY, M
JOURNAL OF CHROMATOGRAPHY, 1990, 519 (01): : 189 - 197
[7] Capillary electrophoretic separation of cis/trans isomers of bis(o-diiminobenzoquinonato)platinum(II) complexes using β-cyclodextrins as the selector
Masuya-Suzuki, Atsuko
Hayashi, Takumi
Tamura, Kosaku
Iki, Nobuhiko
NEW JOURNAL OF CHEMISTRY, 2017, 41 (15) : 7605 - 7612
[8] SEPARATION OF POSITIONAL ISOMERS AND ENANTIOMERS USING CAPILLARY ZONE ELECTROPHORESIS WITH NEUTRAL AND CHARGED CYCLODEXTRINS
SMITH, NW
JOURNAL OF CHROMATOGRAPHY A, 1993, 652 (01) : 259 - 262
[9] Separation of isomers by ultrafiltration using modified cyclodextrins
Yudiarto, A
Dewi, E
Kokugan, T
SEPARATION AND PURIFICATION TECHNOLOGY, 2000, 19 (1-2) : 103 - 112
[10] USE OF NATIVE AND CHEMICALLY MODIFIED CYCLODEXTRINS FOR THE CAPILLARY ELECTROPHORETIC SEPARATION OF ENANTIOMERS
SEPANIAK, MJ
COLE, RO
CLARK, BK
JOURNAL OF LIQUID CHROMATOGRAPHY, 1992, 15 (6-7): : 1023 - 1040

← 1 2 3 4 5 →