IRF1:: a deus ex machina in TH1 differentiation

被引：15
|
作者：
Unutmaz, Derya [1 ]
Vilcek, Jan [1 ]
机构：
[1] NYU Med Ctr, Dept Microbiol, New York, NY 10016 USA
来源：
NATURE IMMUNOLOGY | 2008年 / 9卷 / 01期
关键词：
D O I：
10.1038/ni0108-9
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The cytokines IFN-gamma and IL-12, a long with the transcription factors STAT4 and T-bet, are necessary for driving T(H)1 development. Fresh data now indicate that the transcription factor IRF1 is also essential in this process.
引用
收藏
页码：9 / 10
页数：2
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