Anti-inflammatory activity of compounds isolated from the aerial parts of Abrus precatorius (Fabaceae)

被引：40

作者：

Anam, EM ^{[1
]}

机构：

[1] Univ Calabar, Dept Chem, Calabar, Cross River Sta, Nigeria

来源：

PHYTOMEDICINE | 2001年 / 8卷 / 01期

关键词：

anti-inflammatory activity; croton oil ear model; triterpenoid saponins; oleanen-triol (tetrol); tetraglycosides;

D O I：

10.1078/0944-7113-00001

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two triterpenoid saponins 1 and 2 isolated from the aerial parts of Abrus precatorius and their acetates derivatives, 3 and 4 have been tested for anti-inflammatory activity using the croton oil ear model. All the compounds exhibited anti-inflammatory activity but the acetates showed greater inhibition than the parent compounds.

引用

页码：24 / 27

页数：4

共 12 条

[1] In vivo and in vitro antiinflammatory activity of saikosaponins [J].

Benito, PB ;

Martínez, MJA ;

Sen, AMS ;

Gómez, AS ;

Matellano, LF ;

Contreras, SS ;

Lanza, AMD .

LIFE SCIENCES, 1998, 63 (13) :1147-1156

[2] SONGAROSAPONIN-D - A TRITERPENOID SAPONIN FROM VERBASCUM-SONGARICUM [J].

HARTLEB, I ;

SEIFERT, K .

PHYTOCHEMISTRY, 1994, 35 (04) :1009-1011

[3] A review of the biological and pharmacological activities of saponins [J].

LacailleDubois, MA ;

Wagner, H .

PHYTOMEDICINE, 1996, 2 (04) :363-386

[4]

METZLER D, 1977, BIOCHEMISTRY-US, P707

[5] Studies on the anti-inflammatory activity of rhizomes of Nelumbo nucifera [J].

Mukherjee, PK ;

Saha, K ;

Das, J ;

Pal, M ;

Saha, BP .

PLANTA MEDICA, 1997, 63 (04) :367-369

[6]

RECIO MD, 1995, PLANTA MED, V61, P182, DOI 10.1055/s-2006-958045

[7] TRITERPENE SAPONINS FROM VERBASCUM-SONGARICUM [J].

SEIFERT, K ;

PREISS, A ;

JOHNE, S ;

SCHMIDT, J ;

LIEN, NT ;

LAVAUD, C ;

MASSIOT, G .

PHYTOCHEMISTRY, 1991, 30 (10) :3395-3400

[8]

SHIMIZU K, 1985, CHEM PHARM BULL, V33, P3349

[9]

TAKAGI K, 1980, CHEM PHARM BULL, V28, P1183

[10]

TOKUDA H, 1991, ONCOLOGY, V48, P77

← 1 2 →