Characterization and imaging of lead distribution in bones of lead-exposed birds by ICP-MS and LA-ICP-MS

被引：26

作者：

Ishii, Chihiro ^{[1
]}

Nakayama, Shouta M. M. ^{[1
]}

Kataba, Andrew ^{[1
]}

Ikenaka, Yoshinori ^{[1
,2
]}

Saito, Keisuke ^{[3
]}

Watanabe, Yukiko ^{[3
]}

Makino, Yoshiki ^{[4
]}

Matsukawa, Takehisa ^{[5
]}

Kubota, Ayano ^{[5
]}

Yokoyama, Kazuhito ^{[5
]}

Mizukawa, Hazuki ^{[1
]}

Hirata, Takafumi ^{[4
]}

Ishizuka, Mayumi ^{[1
]}

机构：

[1] Hokkaido Univ, Sch Vet Med, Dept Environm Vet Sci, Lab Toxicol,Kita Ku, Kita18,Nishi9, Sapporo, Hokkaido 0600818, Japan

[2] North West Univ, Unit Environm Sci & Management, Water Res Grp, Private Bag X6001, Potchefstroom, South Africa

[3] Inst Raptor Biomed Japan, 2-2101 Hokuto, Kushiro, Hokkaido 0840922, Japan

[4] Univ Tokyo, Grad Sch Sci, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1130033, Japan

[5] Juntendo Univ, Fac Med, Dept Epidemiol & Environm Hlth, Bunkyo Ku, 2-1-1 Hongo, Tokyo 1138421, Japan

来源：

CHEMOSPHERE | 2018年 / 212卷

基金：

日本学术振兴会;

关键词：

Pb accumulation; Trabecular bone; Bone marrow; Tissue correlation; Eagles; Swans; AMMUNITION SOURCES; CHRONIC TOXICITY; SMELTER WORKERS; SHOT; WATERFOWL; RAPTORS; SPAIN; BIOMARKERS; INGESTION; MARROW;

D O I：

10.1016/j.chemosphere.2018.08.149

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Lead (Pb) poisoning in raptors and water birds is a serious problem in many countries. However, only a small fraction of Pb poisoning has been detected in birds. Bone specimens may be useful indices of Pb exposure because bones contain similar to 90% of the total Pb body burden. The original purpose of this study was to comprehensively analyze Pb accumulation in various bone types using inductively coupled plasma mass spectrometry (ICP-MS). Since our results showed that Pb accumulation differed greatly depending on bone type, a secondary objective was defined, aiming to investigate the fine Pb distribution and its relation to bone structure and bone marrow by using laser ablation (LA)-ICP-MS. Our findings suggested that bone samples (1) consisting of trabecular tissue and (2) those that contain bone marrow could accumulate high levels of Pb following acute exposure. The shorter turnover time of trabecular bone can cause a rapid accumulation of Pb, and bone marrow may have an important role for internal exposure of Pb to bone tissue. Pb is accumulated in bones via blood flow, and bone marrow receives blood from outside the bones. In conclusion, bone samples provide valuable information on Pb exposure and could be useful to investigate and understand mortalities related to suspected Pb poisoning. (C) 2018 Published by Elsevier Ltd.

引用

页码：994 / 1001

页数：8

共 40 条

[1] Embedded lead shot in European starlings Sturnus vulgaris: an underestimated hazard for humans and birds of prey [J].