A practical and versatile approach toward a one-pot synthesis of 2,3-disubstituted 4(3H)-quinazolinones

被引：40

作者：

Dabiri, Minoo ^{[1
]}

Salehi, Peyman ^{[2
]}

Bahramnejad, Mahboobeh ^{[1
]}

Alizadeh, Mohsen ^{[1
]}

机构：

[1] Shahid Beheshti Univ, Dept Chem, Fac Sci, Tehran 1983963113, Iran

[2] Shahid Beheshti Univ, Dept Phytochem, Med Plants & Drugs Res Inst, Tehran 1983963113, Iran

来源：

MONATSHEFTE FUR CHEMIE | 2010年 / 141卷 / 08期

关键词：

Quinazolinone; Heterocycle; Iodine; Multicomponent reaction; Aldehyde; Amine; EFFICIENT SYNTHESIS; 3-COMPONENT SYNTHESIS; DRY MEDIA; (3H)-QUINAZOLIN-4-ONES; QUINAZOLINONES; DERIVATIVES; ANALOGS; IODINE; WATER;

D O I：

10.1007/s00706-010-0341-1

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An effective one-pot three-component route to 4(3H)-quinazolinones from commercially available starting materials is reported. Thus, isatoic anhydride reacted with ammonium acetate or primary amines and aldehydes in the presence of iodine to produce the corresponding quinazolinone derivatives in moderate to good yields.

引用

页码：877 / 881

页数：5

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