The hematopoietic cell transplantation comorbidity index is a predictor of early death and survival in adult acute myeloid leukemia patients

被引：35
作者：
Savic, Aleksandar [1 ]
Kvrgic, Vanja [1 ]
Rajic, Nebojsa [1 ]
Urosevic, Ivana [1 ]
Kovacevic, Dragan [2 ]
Percic, Ivanka [1 ]
Popovic, Stevan [1 ]
机构：
[1] Clin Ctr Vojvodina, Clin Hematol, Novi Sad 21000, Serbia
[2] Inst Cardiovasc Dis Vojvodina, Sremska Kamenica, Serbia
来源：
LEUKEMIA RESEARCH | 2012年 / 36卷 / 04期
关键词：
Acute myeloid leukemia; Comorbidity; Early death; Overall survival; AGE;
D O I：
10.1016/j.leukres.2011.11.021
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The hematopoietic cell transplantation comorbidity index (HCT-CI) is predictive of early death and survival in elderly patients with acute myeloid leukemia (AML). The aim of this study was to determine the prognostic role of the HCT-CI for early death and survival in adult AML patients. In the single-center retrospective study, we analyzed the outcome of 233 adult AML patients. The results indicated that the HCT-CI score is an independent predictor of early death in entire cohort of adult patients with AML. In subgroup analysis, HCT-CI is an independent predictor for early death in elderly patients but not in patients younger than 60 years. A high HCT-CI score predicts shorter survival in adult patients with AML. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码：479 / 482
页数：4
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