Critical appraisal of maxillary swing approach for nasopharyngeal carcinoma

被引:23
作者
Chan, Jimmy Yu Wai [1 ]
Wei, William Ignace [1 ]
机构
[1] Univ Hong Kong, Li Ka Shing Fac Med, Queen Mary Hosp, Div Head & Neck Surg,Dept Surg, Hong Kong, Hong Kong, Peoples R China
关键词
long term results; maxillary swing approach; nasopharyngeal carcinoma; persistent recurrent; surgical salvage; SALVAGE SURGERY; SURGICAL SALVAGE; PHASE-III; CANCER; RADIOTHERAPY; CHEMORADIOTHERAPY; MANAGEMENT; RESECTION; TUMORS;
D O I
10.1517/14728222.2011.637920
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Background: The aim of the current study was to report results of salvage nasopharyngectomy using the maxillary swing approach for persistent or recurrent nasopharyngeal carcinoma after primary treatment. Methods: Between 1989 and 2011, Nasopharyngectomies were performed in 312 patients. Data were composed of retrospective review of records of the first 72 patients followed by a prospective collection of data for the remaining patients. Results: Among the patients, 41 (13.1%) had persistent tumours and 271 (86.9%) had recurrent disease. Curative resection was achieved in 248 (79.5%) patients. All patients survived the operations. The median follow up duration was 34 months. The overall 5-year actuarial local tumour control was 74% and the overall 5-year disease-free survival was 56%. Those with negative resection margins on frozen section and tumour size less than 1.5 cm in diameter had significantly better local tumour control in the nasopharynx as well as disease-free survival. Conclusions: Maxillary swing nasopharyngectomy is an effective salvage procedure for small, persistent or recurrent tumour in the nasopharynx after primary therapy.
引用
收藏
页码:S111 / S117
页数:7
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