Paraneoplastic cerebellar degeneration with fallopian tube adenocarcinoma

被引：10

作者：

Tanaka, Y

Suzuki, N

Takao, M

Ichikawa, A

Susumu, N

Aoki, D

机构：

[1] Keio Univ, Sch Med, Dept Obstet & Gynecol, Shinjuku Ku, Tokyo 1608582, Japan

[2] Yamato Municipal Hosp, Dept Obstet & Gynecol, Kanagawa, Japan

[3] Mihara Mem Hosp, Dept Neurol, Gunma, Japan

[4] Keio Univ, Sch Med, Dept Rehabil, Tokyo, Japan

来源：

GYNECOLOGIC ONCOLOGY | 2005年 / 99卷 / 02期

关键词：

anti-Yo antibody; fallopian tube carcinoma; paraneoplastic cerebellar degeneration;

D O I：

10.1016/j.ygyno.2005.06.064

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background. Paraneoplastic cerebellar degeneration (PCD) is rarely caused by fallopian tube adenocarcinoma. Case. We present a patient with PCD and fallopian tube cancer. Anti-Yo antibody, one of an anti-neuronal antibody, was positive in serum and cerebrospinal fluid. She was also positive for HLA A24, which is common in patients with PCD. Radical surgery did not significantly ameliorate her neurological impairment, although the dysarthria improved slightly. Conclusion. This case highlights the importance of detecting the underlying malignancy in patients with subacute neurological impairment and shows that fallopian tube cancer can potentially cause PCD. (c) 2005 Elsevier Inc. All rights reserved.

引用

页码：500 / 503

页数：4

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