Pigs, pooches and pasteurisation The changing face of brucellosis in Australia

被引:9
作者
Mor, Siobhan M. [1 ,2 ]
Wiethoelter, Anke K. [3 ]
Massey, Peter D. [4 ,5 ]
Robson, Jennifer [6 ]
Wilks, Kathryn [7 ]
Hutchinson, Penny [8 ]
机构
[1] Univ Sydney, Sch Vet Sci, Fac Sci, Sydney, NSW, Australia
[2] Univ Sydney, Inst Infect & Biosecur, Sydney, NSW, Australia
[3] Univ Melbourne, Fac Vet & Agr Sci, Melbourne, Vic, Australia
[4] Hunter New England Populat Hlth, Wallsend, NSW, Australia
[5] James Cook Univ, Coll Med & Dent, Townsville, Qld, Australia
[6] Sullivan Nicolaides Pathol, Brisbane, Qld, Australia
[7] Univ Queensland, Fac Med, Brisbane, Qld, Australia
[8] Darling Downs Hosp & Hlth Serv, Toowoomba, Qld, Australia
关键词
HUMAN TRANSMISSION; PATHOGENESIS; PATHOBIOLOGY; INFECTION;
D O I
10.31128/AFP-08-17-4289
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Background Brucellosis, also known as undulant, Mediterranean or Malta fever, is a systemic infection that causes fever, sweats, arthralgias and myalgias. A globally important disease, brucellosis is re-emerging in Australia in association with feral pig hunting activities. Objective This article aims to provide clinicians with an overview of brucellosis, covering epidemiology, clinical features, diagnosis, management and prevention. Discussion Brucellosis should be suspected in all patients with non-specific, flu-like illness who fall into one of the major risk groups (feral pig hunters, overseas travellers and migrants). Depression is common and often severe, relative to other symptoms. Early diagnosis and treatment are important for preventing complications, which include osteoarticular, genitourinary or, more rarely, neurological or cardiovascular diseases. Diagnosing acute infections is based on serology and blood cultures; imaging and biopsy may be required for diagnosis of focal infections. Dual therapy with doxycycline and gentamicin is the recommended treatment. Relapse occurs in up to 10% of patients. Prevention is achieved through the use of protective gear during hunting (Brucella suis), and avoidance of unpasteurised dairy products in countries where B. melitensis and B. abortus occur in animals.
引用
收藏
页码:99 / 103
页数:5
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