Sensitive electrochemical detection of antigens using gold electrodes functionalized with antibody moieties
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作者:
Ameur, S
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机构:
Ecole Cent Lyon, IFoS, CNRS, UMR 5621, F-69131 Ecully, FranceEcole Cent Lyon, IFoS, CNRS, UMR 5621, F-69131 Ecully, France
Ameur, S
[1
]
Martelet, C
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机构:
Ecole Cent Lyon, IFoS, CNRS, UMR 5621, F-69131 Ecully, FranceEcole Cent Lyon, IFoS, CNRS, UMR 5621, F-69131 Ecully, France
Martelet, C
[1
]
Chovelon, JM
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机构:
Ecole Cent Lyon, IFoS, CNRS, UMR 5621, F-69131 Ecully, FranceEcole Cent Lyon, IFoS, CNRS, UMR 5621, F-69131 Ecully, France
Chovelon, JM
[1
]
Ben Ouada, H
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机构:
Ecole Cent Lyon, IFoS, CNRS, UMR 5621, F-69131 Ecully, FranceEcole Cent Lyon, IFoS, CNRS, UMR 5621, F-69131 Ecully, France
Ben Ouada, H
[1
]
Jaffrezic-Renault, N
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机构:
Ecole Cent Lyon, IFoS, CNRS, UMR 5621, F-69131 Ecully, FranceEcole Cent Lyon, IFoS, CNRS, UMR 5621, F-69131 Ecully, France
Jaffrezic-Renault, N
[1
]
Barbier, D
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机构:
Ecole Cent Lyon, IFoS, CNRS, UMR 5621, F-69131 Ecully, FranceEcole Cent Lyon, IFoS, CNRS, UMR 5621, F-69131 Ecully, France
Barbier, D
[1
]
机构:
[1] Ecole Cent Lyon, IFoS, CNRS, UMR 5621, F-69131 Ecully, France
来源:
EUROSENSORS XII, VOLS 1 AND 2
|
1998年
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D O I:
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中图分类号:
T [工业技术];
学科分类号:
08 ;
摘要:
This paper deals with direct electrochemical detection of antigens using a new method of functionalization of gold electrodes. The antibody was treated in order to form SH groups allowing direct fixation onto gold substrates with coverage factor close to theta = 0.9. An interesting sensitivity for antigen of about few pg/ml can be reached.