An Efficient Glucose Biosensor Based on TiO2 Hollow Sphere Prepared via a Carbon-Sphere Template Method

A glucose biosensor based on hollow sphere TiO2 was prepared via a simple synthesized method that used carbonaceous spheres as template. The studies indicated that the glucose biosensor based on hollow sphere TiO2 is characterized to high surface area, narrow pore size distribution as well as the high sensitivity of 5.64 mA M(-1)cm(-1), which facilitates the direct electron transfer between glucose oxidase (GO(x)) and surface of electrodes. Most importantly, this material display long-time stability and reproducibility and achieved 94% stable current only with 3s. Meanwhile, it still maintains the 70% of current response after two months later, indicating that the hollow sphere TiO2 prepared via a carbon-sphere template method is a promising material for the construction of glucose biosensor and other biologic applications.