Sarcomatoid chordoma: chordoma with a massive malignant spindle-cell component

被引:22
作者
Morimitsu, Y
Aoki, T
Yokoyama, K
Hashimoto, H
机构
[1] Univ Occupat & Environm Hlth, Sch Med, Dept Pathol & Oncol, Yahatanishi Ku, Kitakyushu, Fukuoka 8078555, Japan
[2] Univ Occupat & Environm Hlth, Sch Med, Dept Radiol, Kitakyushu, Fukuoka 8078555, Japan
[3] Natl Kokura Hosp, Dept Orthoped, Kitakyushu, Fukuoka, Japan
关键词
chordoma; sarcomatoid chordoma; transitional feature; sacrum; CT; MRI;
D O I
10.1007/s002560000264
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
We report a case of chordoma containing a spindle cell sarcomatoid component with a gradual transition from conventional chordoma. Immunohistochemically, many tumor cells in both conventional chordoma and sarcomatoid components were positive for cytokeratins (AE1/AE3, CAM5.2) and epithelial membrane antigen as well as vimentin. This report provides a rare example of sarcomatoid chordoma. Familiarity with this type of bone tumor should help to avoid confusion with dedifferentiated chordoma and other spindle cell sarcomas or carcinomas.
引用
收藏
页码:721 / 725
页数:5
相关论文
共 18 条
[1]  
[Anonymous], BONE TUMORS
[2]  
BELZA MG, 1986, CANCER, V58, P1082, DOI 10.1002/1097-0142(19860901)58:5<1082::AID-CNCR2820580517>3.0.CO
[3]  
2-U
[4]  
FUKUDA T, 1992, ACTA PATHOL JAPON, V42, P448
[5]  
HALPERN J, 1984, CANCER, V53, P2661, DOI 10.1002/1097-0142(19840615)53:12<2661::AID-CNCR2820531215>3.0.CO
[6]  
2-6
[7]   LUMBOSACRAL CHORDOMA WITH HIGH-GRADE MALIGNANT CARTILAGINOUS AND SPINDLE CELL COMPONENTS [J].
HRUBAN, RH ;
MAY, M ;
MARCOVE, RC ;
HUVOS, AG .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1990, 14 (04) :384-389
[8]  
HRUBAN RH, 1990, AM J PATHOL, V137, P435
[9]  
KISHIKAWA H, 1974, ACTA PATHOL JAPON, V24, P299
[10]  
KNECHTGES TC, 1970, AM J CLIN PATHOL, V53, P612