Basic Science Review on Adipose Tissue for Clinicians

被引：73
作者：
Brown, Spencer A. [1 ]
Levi, Benjamin
Lequex, Charlotte
Wong, Victor W.
Mojallal, Ali
Longaker, Michael T.
机构：
[1] Univ Texas SW Med Ctr Dallas, Dept Plast Surg, Dallas, TX 75390 USA
来源：
PLASTIC AND RECONSTRUCTIVE SURGERY | 2010年 / 126卷 / 06期
关键词：
MESENCHYMAL STEM-CELLS; STROMAL CELLS; POSTNATAL NEOVASCULARIZATION; ASSISTED LIPOTRANSFER; GENE-EXPRESSION; FAT INJECTION; DIFFERENTIATION; PROFILE; SITE;
D O I：
10.1097/PRS.0b013e3181f44790
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
The recognition that fat contains stem cells has driven further examination into the potential uses of fat and adipose-derived stem cells in a wide number of clinical situations. New information about the harvesting, isolation, and subsequent differentiation properties of isolated adipose-derived stem cells has led to new research into novel tissue-engineered constructs and the transformation of adipose-derived stem cells to induced pluripotent stem cells. Clinically, use of fat grafts and adipose-derived stem cells worldwide and in the United States has dramatically increased in parallel to questions concerning the safety and efficacy of adipose-derived stem cell-based treatments. Currently, the U.S. Food and Drug Administration has not approved the use of isolated adipose-derived stem cells for medical indications. (Plast. Reconstr. Surg. 126: 1936, 2010.)
引用
收藏
页码：1936 / 1946
页数：11
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