The risk factors associated with MERS-CoV patient fatality: A global survey

被引:39
作者
Ahmadzadeh, Jamal [1 ]
Mobaraki, Kazhal [1 ]
Mousavi, Seyed Jalil [2 ]
Aghazadeh-Attari, Javad [1 ]
Mirza-Aghazadeh-Attari, Mohammad [3 ]
Mohebbi, Iraj [1 ]
机构
[1] Urmia Univ Med Sci, Social Determinants Hlth Res Ctr, Orumiyeh, Iran
[2] Urmia Univ Med Sci, Dept Infect Dis, Orumiyeh, Iran
[3] Tabriz Univ Med Sci, Med Philosophy & Hist Res Ctr, Tabriz, Iran
关键词
Middle East respiratory syndrome coronavirus; Epidemiology; Emerging infectious disease; Case fatality rate; EAST RESPIRATORY SYNDROME; SYNDROME CORONAVIRUS INFECTION; SAUDI-ARABIA; SOUTH-KOREA; OUTBREAK; KINGDOM; VIRUS;
D O I
10.1016/j.diagmicrobio.2019.114876
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Risk factors associated with Middle East respiratory syndrome coronavirus (MERS-CoV) infection outcome were established by analyses of WHO data from September 23, 2012 to 18 June 2018. Of the 2220 reported cases, 1408 cases, including 451 MERS-CoV deaths, were analyzed. The case fatality rate was 32% (95% CI: 29.4-34.5). Compared to MERS patients .30 years old, those with >30 years had the adjusted odds ratio estimate for death of 2.38 [95% CI: 1.75-3.22]. This index was 1.43 [95% CI: 1.06-1.92] for Saudi patients in comparison to non-Saudi; 1.76 [95% CI: 1.39-2.22] for patient with comorbidity in comparison to those without comorbidity; 0.58 [95% CI: 0.44-0.75] for those who had close contact to a camel in the past 14 days and 0.42 [95% CI: 031-0.57] for patients with >14 days with onset of signs and hospital admission compared to patients with <= 14 days. (C) 2019 Published by Elsevier Inc.
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