Stress and the brain

被引：53
作者：
Heuser, I [1 ]
Lammers, CH [1 ]
机构：
[1] Univ Hosp Benjamin Franklin, Dept Psychiat, D-14050 Berlin, Germany
来源：
NEUROBIOLOGY OF AGING | 2003年 / 24卷
关键词：
stress; glucocorticoids; HPA system; CRH secretion; PTSD;
D O I：
10.1016/S0197-4580(03)00048-4
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
Stress is a risk factor for a variety of illnesses, involving the same hormones that ensure survival during a period of stress. Although there is a considerable ambiguity in the definition of stress, a useful operational definition is: "anything that induces increased secretion of glucocorticoids". The brain is a major target for glucocorticoids. Whereas the precise mechanism of glucocorticoid-induced brain damage is not yet understood, treatment strategies aimed at regulating abnormal levels of glucocorticoids, are worth examining. (C) 2003 Elsevier Science Inc. All rights reserved.
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收藏
页码：S69 / S76
页数：8
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