Efficient Synthesis of Fluorinated [1,2,4]Triazolo[3,4-b][1,3,4]thiadiazoles

被引：0

作者：

Dhotre, B. K. ^{[1
]}

Raut, S. V. ^{[2
]}

Jagrut, V. B. ^{[1
]}

Patharia, M. A. ^{[3
]}

Pathan, M. A. ^{[2
]}

机构：

[1] Swami Vivekanand Senior Coll, Dept Chem, Mantha 431504, Maharashtra, India

[2] Maulana Azad Coll, Dept Chem, Aurangabad 431001, Maharashtra, India

[3] NFIL Surat, Navin Res & Innovat Ctr, Surat 395002, Gujarat, India

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2021年 / 57卷 / 07期

关键词：

1; 2; 4-triazolo[3; 4-b][1; 3; 4]thiadiazoles; fluorinated acids; cyclization; ANTIMICROBIAL ACTIVITY; BIOLOGICAL-ACTIVITIES; 1,3,4-THIADIAZOLES; 1,3,4-OXADIAZOLE; 1,2,4-TRIAZOLES; DERIVATIVES; DESIGN;

D O I：

10.1134/S1070428021070137

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient synthesis of fluorinated [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives has been achieved by cyclocondensation of 5-substituted 4-amino-1,2,4-triazole-3-thiols with fluoro-substituted aromatic acids using phosphoryl chloride as a cyclizing agent. The synthesized compounds were characterized by spectroscopic techniques, including IR, H-1 NMR, and mass spectra.

引用

页码：1135 / 1140

页数：6

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