Controversies in the management of severe congenital diaphragmatic hernia

被引：28

作者：

Danzer, Enrico ^{[1
,2
]}

Hedrick, Holly L. ^{[1
,2
]}

机构：

[1] Childrens Hosp Philadelphia, Ctr Fetal Diag & Treatment, Philadelphia, PA 19104 USA

[2] Univ Penn, Perelman Sch Med, Philadelphia, PA 19104 USA

来源：

SEMINARS IN FETAL & NEONATAL MEDICINE | 2014年 / 19卷 / 06期

关键词：

Clinical management; Congenital diaphragmatic hernia; Prenatal diagnosis; Pulmonary hypertension; Ventilation; EXTRACORPOREAL MEMBRANE-OXYGENATION; PERSISTENT PULMONARY-HYPERTENSION; FREQUENCY OSCILLATORY VENTILATION; TERM-FOLLOW-UP; TO-HEAD RATIO; FETAL LUNG-VOLUME; NITRIC-OXIDE; LIFE-SUPPORT; HIGH-RISK; HEMORRHAGIC COMPLICATIONS;

D O I：

10.1016/j.siny.2014.10.001

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Despite years of progress in perinatal care, severe congenital diaphragmatic hernia (CDH) remains a clinical challenge. Controversies include almost every facet of clinical care: the definition of severe CDH by prenatal and postnatal criteria, fetal surgical intervention, ventilator management, pulmonary hypertension management, use of extracorporeal membrane oxygenation, surgical considerations, and long-term follow-up. Breakthroughs are likely only possible by sharing of experience, collaboration between institutions and innovative therapies within well-designed multicenter clinical trials. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：376 / 384

页数：9

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