European dissemination of a single OXA-48-producing Klebsiella pneumoniae clone

被引：88
作者：
Potron, A. [1 ,2 ]
Kalpoe, J. [3 ]
Poirel, L. [1 ,2 ]
Nordmann, P. [1 ,2 ]
机构：
[1] Hop Bicetre, Assistance Publ Hop Paris, Serv Bacteriol Virol Hyg,INSERM,Fac Med, U914, K Bicetre, France
[2] Univ Paris Sud, K Bicetre, France
[3] Slotervaart Hosp, Dept Med Microbiol & Infect Prevent, Amsterdam, Netherlands
来源：
CLINICAL MICROBIOLOGY AND INFECTION | 2011年 / 17卷 / 12期
关键词：
Carbapenems; class D ss-lactamase; Klebsiella pneumoniae; OXA-48; ST395; OXACILLINASE-MEDIATED RESISTANCE; OXA-48; BETA-LACTAMASE; PLASMID; SPREAD; CARBAPENEMASE; IMIPENEM;
D O I：
10.1111/j.1469-0691.2011.03669.x
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
A Klebsiella pneumoniae isolate with decreased susceptibility to carbapenems was isolated in April 2011 in a hospital in Amsterdam (the Netherlands) and later found to be the source of an important outbreak in a Rotterdam hospital. The strain, belonging to sequence type (ST) 395, carried the blaOXA-48 gene located onto a c 62-kb conjugative plasmid, together with the extended-spectrum beta-lactamase gene blaCTX-M-15. It was closely related or identical to other OXA-48-positive Klebsiella pneumoniae isolates belonging to the same ST type and identified in France and Morocco. This study sheds light on the European dissemination of a single OXA-48 K. pneumoniae clone.
引用
收藏
页码：E24 / E26
页数：3
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