Chemical composition and antimicrobial activity of the essential oil from Satureja horvatii Silic (Lamiaceae)

被引:19
作者
Lakusic, Branislava [1 ]
Ristic, Mihailo [2 ]
Slavkovska, Violeta [1 ]
Stankovic, Jelena Antic [3 ]
Milenkovic, Marina [3 ]
机构
[1] Univ Belgrade, Fac Pharm, Inst Bot, Belgrade 11000, Serbia
[2] Inst Med Plant Res Josif Pancic, Belgrade 11000, Serbia
[3] Univ Belgrade, Fac Pharm, Inst Microbiol, Belgrade 11000, Serbia
关键词
Satureja horvatii; endemic species; essential oil; GC-MS; antimicrobial activity;
D O I
10.2298/JSC0807703L
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The present paper describes the chemical composition and antimicrobial activity of the essential oil of the endemic species Satureja horvatii Silic, collected in Montenegro. The essential oil was obtained from the aerial parts of the plant by hydrodistillation and analyzed by GC-MS. From the 34 compounds representing 100 % of the oil, the major compound was the phenolic monoterpene thymol (63.37 %). The oil contained smaller amounts of gamma-terpinene (7.49 %), carvacrol methyl ether (4.92 %), carvacrol (4.67 %), p-cymene (4.52%), alpha-terpinene (1.81 %), borneol (1.58 %), alpha-thujene (1.56 %), beta-caryophyllene (1.55 %) and beta-myrcene (1.44 %). The antimicrobial activity of the essential oil of S. horvatii was evaluated using the agar diffusion and broth microdilution methods. The essential oil exhibited antimicrobial activity to varying degrees against all the tested strains. The maximum activity of S. horvatii oil was observed against Gram-positive bacteria (Micrococcus luteus, Staphylococcus epidermidis, Staphylococcus aureus and Enterococcus faecalis) and against the yeast (Candida albicans). The oil exhibited moderate activity against the Gram-negative bacteria Escherichia coli and Klebsiella pneumoniae and weak activity against Pseudomonas aeruginosa. This study confirms that the essential oil of S. horvatii possesses antimicrobial activities in vitro against medically important pathogens.
引用
收藏
页码:703 / 711
页数:9
相关论文
共 27 条
[1]  
Adams R. P., 2007, Identification of essential oils components by gas chromatography. Quadruple mass spectroscopy
[2]   Antibacterial activity and composition of essential oils from Origanum, Thymbra and Satureja species with commercial importance in Turkey [J].
Baydar, H ;
Sagdiç, O ;
Özkan, G ;
Karadogan, T .
FOOD CONTROL, 2004, 15 (03) :169-172
[3]  
Bezic N., 1999, Acta Botanica Croatica, V58, P99
[4]   Antioxidant and antimicrobial activity of the essential oil and methanol extracts of Achillea millefolium subsp millefolium Afan. (Asteraceae) [J].
Candan, F ;
Unlu, M ;
Tepe, B ;
Daferera, D ;
Polissiou, M ;
Sökmen, A ;
Akpulat, HA .
JOURNAL OF ETHNOPHARMACOLOGY, 2003, 87 (2-3) :215-220
[5]   Antimicrobial properties of essential oil of Satureja montana L. on pathogenic and spoilage yeasts [J].
Ciani, M ;
Menghini, L ;
Mariani, F ;
Pagiotti, R ;
Menghini, A ;
Fatichenti, F .
BIOTECHNOLOGY LETTERS, 2000, 22 (12) :1007-1010
[6]   Antimicrobial agents from plants: antibacterial activity of plant volatile oils [J].
Dorman, HJD ;
Deans, SG .
JOURNAL OF APPLIED MICROBIOLOGY, 2000, 88 (02) :308-316
[7]   Antimicrobial susceptibility and frequency of occurrence of clinical blood isolates in Europe from the SENTRY Antimicrobial Surveillance Program, 1997 and 1998 [J].
Fluit, AC ;
Jones, ME ;
Schmitz, FJ ;
Acar, J ;
Gupta, R ;
Verhoef, J .
CLINICAL INFECTIOUS DISEASES, 2000, 30 (03) :454-460
[8]   Evaluation of antilisterial action of cilantro oil on vacuum packed ham [J].
Gill, AO ;
Delaquis, P ;
Russo, P ;
Holley, RA .
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 2002, 73 (01) :83-92
[9]   In vitro antibacterial, antifungal, and antioxidant activities of the essential oil and methanol extracts of herbal parts and callus cultures of Satureja hortensis L. [J].
Güllüce, M ;
Sökmen, M ;
Daferera, D ;
Agar, G ;
Özkan, H ;
Kartal, N ;
Polissiou, M ;
Sökmen, A ;
Sahin, F .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2003, 51 (14) :3958-3965
[10]   Antispasmodic and anti-diarrhoeal effect of Satureja hortensis L. essential oil [J].
Hajhashemi, V ;
Sadraei, H ;
Ghannadi, AR ;
Mohseni, M .
JOURNAL OF ETHNOPHARMACOLOGY, 2000, 71 (1-2) :187-192