High genetic diversity including potential new subtypes of hepatitis C virus genotype 6 in Lao People's Democratic Republic

被引：33

作者：

Huebschen, J. M. ^{[1
]}

Jutavijittum, P. ^{[2
]}

Thammavong, T. ^{[3
]}

Samountry, B. ^{[4
]}

Yousukh, A. ^{[2
]}

Toriyama, K. ^{[5
]}

Sausy, A. ^{[1
]}

Muller, C. P. ^{[1
]}

机构：

[1] Ctr Rech Publ Sante, Inst Immunol, Lab Natl Sante, L-1950 Luxembourg, Luxembourg

[2] Chiang Mai Univ, Dept Pathol, Fac Med, Chiang Mai 50000, Thailand

[3] Natl Blood Transfus Ctr, Viangchan, Lao PDR, Laos

[4] Univ Hlth Sci, Dept Pathol, Fac Med Sci, Viangchan, Lao PDR, Laos

[5] Nagasaki Univ, Dept Pathol, Inst Trop Med, Nagasaki 852, Japan

来源：

CLINICAL MICROBIOLOGY AND INFECTION | 2011年 / 17卷 / 12期

关键词：

Genotype; HCV; Laos; phylogeny; subtype; COMPLETE GENOMES; BLOOD-DONORS; CHINA; INFECTION; SEQUENCE;

D O I：

10.1111/j.1469-0691.2011.03665.x

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Sera from 105 anti-HCV-positive first-time blood donors collected in 2004, 2005 and 2008 in different provinces in Laos were investigated by PCR. Forty-five samples were positive for HCV (42.86%); two belonged to subtype 1b (2/45, 4.4%) and all others to genotype 6 (43/45, 95.6%), including subtypes 6b, 6h, 6k, 6l, 6n and 6q. Three groups of sequences were not clearly attributable to any genotype 6 subtype, two of which may be regarded as candidates for new subtypes of genotype 6. Two samples were mixed infected with different subtypes or clusters of genotype 6 viruses.

引用

页码：E30 / E34

页数：5

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