Temoporfin (Foscan®, 5,10,15,20-Tetra(m-hydroxyphenyl)chlorin)-A Second-generation Photosensitizer

被引：260

作者：

Senge, Mathias O. ^{[1
,2
]}

Brandt, Johan C. ^{[2
]}

机构：

[1] St James Hosp, Trinity Ctr Hlth Sci, Inst Mol Med, Trinity Coll Dublin, Dublin 8, Ireland

[2] Trinity Coll Dublin, Sch Chem, SFI Tetrapyrrole Lab, Dublin 2, Ireland

来源：

PHOTOCHEMISTRY AND PHOTOBIOLOGY | 2011年 / 87卷 / 06期

基金：

爱尔兰科学基金会;

关键词：

MEDIATED PHOTODYNAMIC THERAPY; SQUAMOUS-CELL CARCINOMA; TETRA-HYDROXYPHENYL-CHLORIN; MALIGNANT PLEURAL MESOTHELIOMA; M-TETRAHYDROXYPHENYL CHLORIN; LASER-INDUCED FLUORESCENCE; HUMAN TUMOR XENOGRAFTS; HIGH-GRADE DYSPLASIA; RESONANCE MASS-SPECTROMETRY; OPTIMIZING LIGHT DOSIMETRY;

D O I：

10.1111/j.1751-1097.2011.00986.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This review traces the development and study of the second-generation photosensitizer 5,10,15,20-tetra(m-hydroxyphenyl)chlorin through to its acceptance and clinical use in modern photodynamic (cancer) therapy. The literature has been covered up to early 2011.

引用

页码：1240 / 1296

页数：57