Emergence of Mycoplasma genitalium strains showing mutations associated with macrolide and fluoroquinolone resistance in the region Dresden, Germany

被引：41
作者：
Dumke, Roger [1 ]
Thuermer, Alexander [1 ]
Jacobs, Enno [1 ]
机构：
[1] Tech Univ Dresden, Inst Med Microbiol & Hyg, Dresden, Germany
来源：
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2016年 / 86卷 / 02期
关键词：
Mycoplasma genitalium; Macrolide resistance; Quinolone resistance; 23S rRNA mutation; Topoisomerase mutation; Genotyping; NONGONOCOCCAL URETHRITIS; FAILURE; INFECTION; SEQUENCES;
D O I：
10.1016/j.diagmicrobio.2016.07.005
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Among 323 specimens from male patients with symptoms of non-gonococcal urethritis, Mycoplasma genitalium was detected in 19 samples by real-time PCR Mutations of 23S rRNA gene associated with macrolide resistance were confirmed in 10 strains. Amino acid changes at positions 81 and 83 of ParC protein were demonstrated indicating quinolone resistance of two strains. (C) 2016 Elsevier Inc. All rights reserved.
引用
收藏
页码：221 / 223
页数：3
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