Synthesis of 3-[6-(2-amino-ethoxy)-3-methyl-5-(3-morpholin-4-yl-propionyl)-benzofuran-2 carbonyl]-chromen-2-one under microwave irradiation conditions

被引：2

作者：

Kuarm, B. Suresh ^{[1
]}

Kumar, V. Naveen ^{[1
]}

Madhav, J. Venu ^{[1
]}

Rajitha, B. ^{[1
]}

机构：

[1] Natl Inst Technol, Dept Chem, Warangal 506004, Andhra Pradesh, India

来源：

GREEN CHEMISTRY LETTERS AND REVIEWS | 2011年 / 4卷 / 02期

关键词：

mannich base; benzofuran-2-carbonyl chromene-2-one; microwave irradiation; ONE-POT SYNTHESIS; AGENTS; BASES;

D O I：

10.1080/17518253.2010.506450

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(5-Acetyl-6-hydroxy-3-methylbenzofuran-2-carbonyl)-chromene-2-one, paraformaldehyde, and morpholine furnished the mannich base 3-[6-hydroxy 3-methyl-5-(3-morpholin-4-yl-propionyl)-benzofuran-2 carbonyl]chromen-2-one. This mannich base is irradiated with various chloro-substituted amines afforded 3-[6-(2-aminoethoxy)-3-methyl-5-(3-morpholin-4-yl-propionyl)-benzofuran-2 carbonyl]-chromen-2-one in good yields. [GRAPHICS] .

引用

页码：97 / 101

页数：5

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