An imidazole alkaloid and other constituents from Pilocarpus trachyllophus

被引：24

作者：

AndradeNeto, M

Mendes, PH

Silveira, ER

机构：

[1] MERCK SA,IND QUIM,LAB PESQUISAS FITOQUIM,RIO JANEIRO,BRAZIL

[2] UNIV FED CEARA,DEPT QUIM ORGAN & INORGAN,LAB PROD NAT,CURSO POSGRADUACAO QUIM ORGAN,BR-60021970 FORTALEZA,CEARA,BRAZIL

来源：

PHYTOCHEMISTRY | 1996年 / 42卷 / 03期

关键词：

Pilocarpus trachyllophus; Rutaceae; Jaborandi; flavonoid glycoside; aliphatic ketones; isobutylamide;

D O I：

10.1016/0031-9422(95)00852-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Roots of Pilocarpus trachyllophus yielded (-)-episesamin, hesperidin, tridecan-2-one, 1-hydroxy-tridecan-2-one, N-isobutyl-deca-2(E),4(E)-dienamide, pilocarpine and a new imidazole alkaloid, 13-nor-7(11)-dehydropilocarpine. Except for pilocarpine and tridecan-2-one, this is the first report of these substances in the genus Pilocarpus. Structural determinations were accomplished by spectroscopic analysis, particularly two-dimensional NMR, chemical interconversion and, where appropriate, comparison with literature data.

引用

页码：885 / 887

页数：3

共 13 条

[1]

COSTA OA, 1968, REV BRASILEIRA FARMA, V6, P324

[2] C-13 AND H-1-NMR INVESTIGATION OF PILOCARPINE HYDROCHLORIDE IN WATER SOLUTION [J].