Advances in Cancer Therapeutics: Conventional Thermal Therapy to Nanotechnology-Based Photothermal Therapy

被引:66
作者
Kumari, Sangeeta [1 ]
Sharma, Nilesh [2 ]
Sahi, Shivendra V. [1 ]
机构
[1] Univ Sci, Dept Biol Sci, Philadelphia, PA 19104 USA
[2] Western Kentucky Univ, Dept Biol, 1906 Coll Hts Blvd, Bowling Green, KY 42101 USA
关键词
cancer; photothermal therapy; laser; clinical trial; magnetic nanoparticles; graphene; nanotubes; quantum dots; nanosheets; nanomaterials; INTENSITY FOCUSED ULTRASOUND; MAGNETIC NANOPARTICLE HYPERTHERMIA; GOLD NANOPARTICLES; CARBON NANOTUBES; QUANTUM DOTS; RADIOFREQUENCY ABLATION; GRAPHENE OXIDE; IN-VITRO; TUMOR ABLATION; METAL NANOPARTICLES;
D O I
10.3390/pharmaceutics13081174
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
In this review, advancement in cancer therapy that shows a transition from conventional thermal therapies to laser-based photothermal therapies is discussed. Laser-based photothermal therapies are gaining popularity in cancer therapeutics due to their overall outcomes. In photothermal therapy, light is converted into heat to destruct the various types of cancerous growth. The role of nanoparticles as a photothermal agent is emphasized in this review article. Magnetic, as well as non-magnetic, nanoparticles have been effectively used in the photothermal-based cancer therapies. The discussion includes a critical appraisal of in vitro and in vivo, as well as the latest clinical studies completed in this area. Plausible evidence suggests that photothermal therapy is a promising avenue in the treatment of cancer.
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收藏
页数:23
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