Cellulose-Based Nanomaterials Advance Biomedicine: A Review

被引:95
作者
Abdelhamid, Hani Nasser [1 ,2 ]
Mathew, Aji P. [1 ]
机构
[1] Stockholm Univ, Dept Mat & Environm Chem, SE-10691 Stockholm, Sweden
[2] Assiut Univ, Dept Chem, Adv Multifunct Mat Lab, Fac Sci, Assiut 71515, Egypt
关键词
cellulose; biomedical; wound healing; drug delivery; antibacterial; tissue engineering; CALCIUM-DEFICIENT HYDROXYAPATITE; ARTIFICIAL BLOOD-VESSELS; NANO BACTERIAL CELLULOSE; IN-VITRO; NANOCRYSTALLINE CELLULOSE; MECHANICAL-PROPERTIES; NANOFIBRILLATED CELLULOSE; SURFACE FUNCTIONALIZATION; ANTIBACTERIAL ACTIVITY; ANTIMICROBIAL ACTIVITY;
D O I
10.3390/ijms23105405
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
There are various biomaterials, but none fulfills all requirements. Cellulose biopolymers have advanced biomedicine to satisfy high market demand and circumvent many ecological concerns. This review aims to present an overview of cellulose knowledge and technical biomedical applications such as antibacterial agents, antifouling, wound healing, drug delivery, tissue engineering, and bone regeneration. It includes an extensive bibliography of recent research findings from fundamental and applied investigations. Cellulose-based materials are tailorable to obtain suitable chemical, mechanical, and physical properties required for biomedical applications. The chemical structure of cellulose allows modifications and simple conjugation with several materials, including nanoparticles, without tedious efforts. They render the applications cheap, biocompatible, biodegradable, and easy to shape and process.
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页数:36
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