Cbfa1 in bone development

被引:106
作者
Komori, T [1 ]
Kishimoto, T [1 ]
机构
[1] Japan Sci & Technol Corp, Osaka Univ, Sch Med, Dept Med 3, Suita, Osaka 5650871, Japan
关键词
D O I
10.1016/S0959-437X(98)80123-8
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
A factor fundamental to bone formation has been identified. Gene targeting shows that core-binding factor al (Cbfa1) plays an essential role in bone formation and osteoblast differentiation. Thus, it is now possible to begin examining the molecular mechanisms of bone formation - especially osteoblast differentiation.
引用
收藏
页码:494 / 499
页数:6
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