Palladium-Catalyzed Stereoselective Difunctionalization of Bicyclic Alkenes with Organoammonium Salts and Organoboronic Compounds

被引：8

作者：

Tang, Yuanyuan ^{[1
]}

Liu, Kuan ^{[1
]}

Zhang, Jinjin ^{[1
]}

Liu, Long ^{[1
]}

Huang, Tianzeng ^{[1
]}

Li, Chunya ^{[1
]}

Tang, Zhi ^{[1
]}

Chen, Tieqiao ^{[1
]}

机构：

[1] Hainan Univ, Hainan Prov Fine Chem Engn Res Ctr, Key Lab Minist Educ Adv Mat Trop Isl Resources, Hainan Prov Key Lab Fine Chem, Haikou 570228, Hainan, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2021年 / 86卷 / 17期

关键词：

QUATERNARY AMMONIUM-SALTS; CROSS-COUPLING REACTIONS; PROGRESS; ARYL; FUNCTIONALIZATION; TRANSFORMATIONS; CARBOACYLATION; ELECTROPHILES; BORYLATION; CLEAVAGE;

D O I：

10.1021/acs.joc.1c01339

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A palladium-catalyzed difunctionalization of bicyclic alkenes with organoammonium salts and organoboronic compounds was reported. A wide range of functionalized cyclic products, including those bearing functional groups, were produced stereoselectively in good to excellent yields. The gram-scale experiment, one-pot operation, and synthetic application of beta-borylated products further demonstrated the synthetic value of this new reaction in organic synthesis.

引用

页码：11937 / 11947

页数：11

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