Atypical hearing loss in women with breast cancer receiving adjuvant treatment

被引：8
作者：
Jenkins, V. [1 ]
Beveridge, H. [1 ]
Low, R. [2 ]
Mitra, S. [3 ]
机构：
[1] Univ Sussex, Brighton & Sussex Med Sch, Canc Res UK Psychosocial Oncol Grp, Falmer BN1 9QG, E Sussex, England
[2] Royal Sussex Cty Hosp, Dept Audiol, Brighton BN2 5BE, E Sussex, England
[3] Royal Sussex Cty Hosp, Sussex Canc Ctr, Brighton BN2 5BE, England
来源：
BREAST | 2006年 / 15卷 / 03期
基金：
英国医学研究理事会;
关键词：
breast cancer; chemotherapy; endocrine therapy; atypical hearing loss;
D O I：
10.1016/j.breast.2005.06.005
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
There are no reports of adjuvant treatments for early breast cancer causing hearing loss. Yet in this exploratory study 14/16 women who had received Fluorouracil, Epirubicin and Cyclophosphamide (FEC) chemotherapy regimen, 11 of whom also received endocrine treatment, had reduced hearing sensitivity, with 9/16 being atypical. It is not clear whether this finding is related to oestrogen reduction and/or ototoxicity but a more detailed investigation in this area is warranted given the large number of women with breast cancer who receive adjuvant treatments. (C) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码：448 / 451
页数：4
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