Review of the Research Progress of Human Brain Oxygen Extraction Fraction by Magnetic Resonance Imaging

被引：1

作者：

Jian, Zini ^{[1
]}

Wang, Xianpei ^{[2
]}

Tian, Meng ^{[2
]}

Liu, Yufei ^{[3
]}

Yao, Hongtai ^{[2
]}

Gong, Li ^{[2
]}

Li, Bowen ^{[2
]}

机构：

[1] Wuhan Text Univ, Sch Elect & Elect Engn, Wuhan 430200, Peoples R China

[2] Wuhan Univ, Elect Informat Sch, Wuhan 430072, Peoples R China

[3] Hebei Xiongan Taixin Technol Co Ltd, Baoding 071000, Peoples R China

来源：

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY | 2022年 / 2022卷

基金：

中国国家自然科学基金;

关键词：

CEREBRAL METABOLIC-RATE; DEOXYGENATED BLOOD-VOLUME; QUANTITATIVE MEASUREMENTS; FLOW; OEF; PET; MRI; SIGNAL; QUANTIFICATION; VALIDATION;

D O I：

10.1155/2022/4554271

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In recent years, the incidence of cerebrovascular diseases (CVD) is increasing, which seriously endangers human health. The study on hemodynamics of cerebrovascular disease can help us to understand, prevent, and treat the disease. As one of the important parameters of human cerebral hemodynamics and tissue metabolism, OEF (oxygen extraction fraction) is of great value in central nervous system diseases. The use of BOLD (blood oxygen level dependent) effect offers the possibility to study cerebral hemodynamic and metabolic characteristics by MRI (magnetic resonance imaging) measurements. Therefore, this paper reviews the hemodynamic parameters of brain tissue, discusses the principles and methods of quantitative BOLD-based MRI measurements of OEF, and discusses the advantages and disadvantages of each method.

引用

页数：13

共 78 条

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