Peritoneal dialysis for patients suffering from severe heart failure

被引:23
作者
Sotirakopoulos, N. G. [1 ]
Kalogiannidou, I. M. [1 ]
Tersi, M. E. [1 ]
Mavromatidis, K. S. [1 ]
机构
[1] Gen Hosp Komotini, Renal Dept, Komotini, Greece
关键词
congestive heart failure; peritoneal dialysis; icodextrin; survival rate; quality of life; chronic renal disease; chronic renal failure; QUALITY-OF-LIFE; ICODEXTRIN; MANAGEMENT; ULTRAFILTRATION; MORTALITY; EFFICACY; THERAPY;
D O I
10.5414/CN107026
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Over a period of 6.5 years, we treated 19 patients, all of whom suffered from severe heart failure and various stages of chronic kidney disease, excluding those with end-stage kidney failure. Before peritoneal catheter implantation, all patients had ascites, dyspnea, orthopnea, and an ejection fraction ranging from 20 to 45%. Seven of them (7/19) were able to take care of themselves, 9/19 needed assistance for their daily activities, and the remaining 3 were bedridden. All of them needed hospitalization 1 - 3 times/month during the year before the initiation of continuous ambulatory peritoneal dialysis (CAPD). With peritoneal dialysis, daily ultrafiltrate volume ranged from 500 to 3,000 ml and, after an average of 2 months of peritoneal dialysis, body weight decreased significantly (74.7 +/- 13 vs. 69.7 +/- 10.2, p = 0.02). At the same time, diuresis improved significantly, and this allowed a reduction in the dose of diuretics. Dyspnea and orthopnea improved significantly in all patients. The patients' degree of self-care and ability to sleep lying flat improved significantly as the need for hospitalization declined. Before peritoneal dialysis, patients were hospitalized for 5 - 20 days/month for pulmonary edema or over-hydration, whereas with peritoneal dialysis, nobody was hospitalized for these causes (chi(2), p = 0.0001). Ejection fraction also improved in all of them (28.6 +/- 8.6 vs. 36.8 +/- 12.5%, p = 0.0001). Actual survival of our patients ranged from 6 to 86 months (mean +/- SD = 24.6 +/- 20.8). Actuarial survival was 68% at 1 year and 42% at 2 years. During peritoneal dialysis we observed only two episodes of peritonitis. Four patients developed a severe episode of hypotension during implantation of the catheters from the sudden removal of 4 - 6 l of ascitic fluid. We conclude that peritoneal dialysis is a good method for the treatment of congestive heart failure because it increases the quality of life and life expectancy in patients with poor prognosis.
引用
收藏
页码:124 / 129
页数:6
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