Isolation and purification of glycyrrhizic acid with solvent extraction

被引：32

作者：

Niu, GG ^{[1
]}

Xie, YC ^{[1
]}

Lou, HF ^{[1
]}

Liu, HZ ^{[1
]}

机构：

[1] Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Lab Separat Sci & Engn, Beijing 100080, Peoples R China

来源：

SEPARATION AND PURIFICATION TECHNOLOGY | 2005年 / 44卷 / 03期

基金：

中国国家自然科学基金;

关键词：

liquorice; glycyrrhizic acid; solvent extraction; purification;

D O I：

10.1016/j.seppur.2004.05.011

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

Solvent extraction of glycyrrhizic acid (GA) from liquorice leaching solution was studied with tributyl phosphate, trialkylphosphine oxide, n-hexanol and 2-ethyl-hexanol as extractants. The results showed that GA was easily extracted into the organic phase in molecular state by the formation of hydrogen bond. pH was the key factor influencing the selectivity during extraction and stripping. The extraction mechanism was studied with transmitting electron microscopy and analysis of solute distribution. It was deduced that glycyrrhizic acid was extracted into the organic solvent in the form of molecular aggregation rather than as single molecules. (C) 2004 Elsevier B.V. All rights reserved.

引用

页码：189 / 196

页数：8

共 23 条

[21]

张平, 1994, [华东理工大学学报. 自然科学版, Journal of East China University of Science and Technoloy. Natural Sciences Edition], V20, P148

[22]

王大为, 1995, [华东理工大学学报. 自然科学版, Journal of East China University of Science and Technoloy. Natural Sciences Edition], V21, P548

[23]

王大为, 1992, [华东理工大学学报. 自然科学版, Journal of East China University of Science and Technoloy. Natural Sciences Edition], V18, P718

← 1 2 3 →