In vitro differentiation of mouse embryonic stem cells into cardiac cells

被引：0
作者：
Pall, Emoke [1 ]
Lichner, Zsuzsanna [2 ]
Gocza, Elen [2 ]
Groza, I. S. [1 ]
Cenariu, M.
Olga, Soritau [3 ]
Tomuleasa, C. [4 ]
机构：
[1] Univ Agr Sci & Vet Med Cluj Napoca Romania, Fac Vet Med, Cluj Napoca 400372, Romania
[2] Agr Biotechnol Ctr, H-2101 Godollo, Hungary
[3] Inst Oncol, Cluj Napoca, Romania
[4] Univ Med & Pharm Luliu Hatieganu, Cluj Napoca, Romania
来源：
ROMANIAN BIOTECHNOLOGICAL LETTERS | 2011年 / 16卷 / 03期
关键词：
mouse; embryonic stem cells; pluripotent; cardiac differentiation; BONE MORPHOGENETIC PROTEINS; LEUKEMIA INHIBITORY FACTOR; GROWTH-FACTOR; CARDIOMYOCYTE DIFFERENTIATION; FUNCTIONAL-PROPERTIES; GENE-EXPRESSION; RETINOIC ACID; BODIES; BODY; INSULIN;
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
In its evolution, medicine has imposed a batch of experimental systems that have tried to explain the miracle through which a fertilized cell transformed in blastocyst lies at the basis of all the specialized tissues that form an organism. It seems that the answers derived from these studies intensified the number of medical questions, engendering a new research theme: the embryonic stem cells. Embryonic stem cells are derived from preimplantation blastocyst. they are pluripotent cells and they are able to differentiate to different cell lines. This review aims to structure different differentiation protocols most commonly used by different specialists in the field, specifying the role of inducer substances and of the specific methods and substrates used.
引用
收藏
页码：6170 / 6180
页数：11
相关论文
共 111 条
[51]  
Kurosawa H, 2003, J BIOSCI BIOENG, V96, P409, DOI 10.1263/jbb.96.409
[52]   Methods for inducing embryoid body formation:: In vitro differentiation system of embryonic stem cells [J].
Kurosawa, Hiroshi .
JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 2007, 103 (05) :389-398
[53]  
KURSAD T, 2002, EMBRYONIC STEM CELLS, P185
[54]  
Leahy A, 1999, J EXP ZOOL, V284, P67, DOI 10.1002/(SICI)1097-010X(19990615)284:1<67::AID-JEZ10>3.0.CO
[55]  
2-O
[56]   Elevated blood pressure and enhanced myocardial contractility in mice with severe IGF-1 deficiency [J].
Lembo, G ;
Rockman, HA ;
Hunter, JJ ;
Steinmetz, H ;
Koch, WJ ;
Ma, L ;
Prinz, MP ;
Ross, J ;
Chien, KR ;
PowellBraxton, L .
JOURNAL OF CLINICAL INVESTIGATION, 1996, 98 (11) :2648-2655
[57]   Endothelial cells derived from human embryonic stem cells [J].
Levenberg, S ;
Golub, JS ;
Amit, M ;
Itskovitz-Eldor, J ;
Langer, R .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (07) :4391-4396
[58]   Lineage choice and differentiation in mouse embryos and embryonic stem cells [J].
Loebel, DAF ;
Watson, CM ;
De Young, A ;
Tam, PPL .
DEVELOPMENTAL BIOLOGY, 2003, 264 (01) :1-14
[59]  
Magyar JP, 2001, ANN NY ACAD SCI, V944, P135
[60]  
MERWIN JR, 1991, AM J PATHOL, V138, P37
12345678910