In vitro differentiation of mouse embryonic stem cells into cardiac cells

被引：0

作者：

Pall, Emoke ^{[1
]}

Lichner, Zsuzsanna ^{[2
]}

Gocza, Elen ^{[2
]}

Groza, I. S. ^{[1
]}

Cenariu, M.

Olga, Soritau ^{[3
]}

Tomuleasa, C. ^{[4
]}

机构：

[1] Univ Agr Sci & Vet Med Cluj Napoca Romania, Fac Vet Med, Cluj Napoca 400372, Romania

[2] Agr Biotechnol Ctr, H-2101 Godollo, Hungary

[3] Inst Oncol, Cluj Napoca, Romania

[4] Univ Med & Pharm Luliu Hatieganu, Cluj Napoca, Romania

来源：

ROMANIAN BIOTECHNOLOGICAL LETTERS | 2011年 / 16卷 / 03期

关键词：

mouse; embryonic stem cells; pluripotent; cardiac differentiation; BONE MORPHOGENETIC PROTEINS; LEUKEMIA INHIBITORY FACTOR; GROWTH-FACTOR; CARDIOMYOCYTE DIFFERENTIATION; FUNCTIONAL-PROPERTIES; GENE-EXPRESSION; RETINOIC ACID; BODIES; BODY; INSULIN;

D O I：

暂无

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

In its evolution, medicine has imposed a batch of experimental systems that have tried to explain the miracle through which a fertilized cell transformed in blastocyst lies at the basis of all the specialized tissues that form an organism. It seems that the answers derived from these studies intensified the number of medical questions, engendering a new research theme: the embryonic stem cells. Embryonic stem cells are derived from preimplantation blastocyst. they are pluripotent cells and they are able to differentiate to different cell lines. This review aims to structure different differentiation protocols most commonly used by different specialists in the field, specifying the role of inducer substances and of the specific methods and substrates used.

引用

页码：6170 / 6180

页数：11

共 111 条

[1] Endoderm-specific gene expression in embryonic stem cells differentiated to embryoid bodies [J].

Abe, K ;

Niwa, H ;

Iwase, K ;

Takiguchi, M ;

Mori, A ;

Abe, S ;

Abe, K ;

Yamamura, K .

EXPERIMENTAL CELL RESEARCH, 1996, 229 (01) :27-34

[2] Stem cell therapy - Present status [J].

Aejaz, H. M. ;

Aleem, A. K. ;

Parveen, N. ;

Khaja, M. N. ;

Narusu, M. Lakshmi ;

Habibullah, C. M. .

TRANSPLANTATION PROCEEDINGS, 2007, 39 (03) :694-699

[3]

AKHURST R J, 1990, Progress in Growth Factor Research, V2, P153, DOI 10.1016/0955-2235(90)90002-2

[4]

Alenzi Faris Q, 2010, Lab Hematol, V16, P53, DOI 10.1532/LH96.10010

[5] Insulin production by human embryonic stem cells [J].

Assady, S ;

Maor, G ;

Amit, M ;

Itskovitz-Eldor, J ;

Skorecki, KL ;

Tzukerman, M .

DIABETES, 2001, 50 (08) :1691-1697

[6] The effect of matrix composition of 3D constructs on embryonic stem cell differentiation [J].

Battista, S ;

Guarnieri, D ;

Borselli, C ;

Zeppetelli, S ;

Borzacchiello, A ;

Mayol, L ;

Gerbasio, D ;

Keene, DR ;

Ambrosio, L ;

Netti, PA .

BIOMATERIALS, 2005, 26 (31) :6194-6207

[7] Stem cell differentiation requires a paracrine pathway in the heart [J].

Behfar, A ;

Zingman, LV ;

Hodgson, DM ;

Rauzier, JM ;

Kane, GC ;

Terzic, A ;

Pucéat, M .

FASEB JOURNAL, 2002, 16 (12) :1558-1566

[8] TGFβ2 and TGFβ3 have separate and sequential activities during epithelial-mesenchymal cell transformation in the embryonic heart [J].

Boyer, AS ;

Ayerinskas, II ;

Vincent, EB ;

McKinney, LA ;

Weeks, DL ;

Runyan, RB .

DEVELOPMENTAL BIOLOGY, 1999, 208 (02) :530-545

[9] Temporal and distinct TGFβ ligand requirements during mouse and avian endocardial cushion morphogenesis [J].

Camenisch, TD ;

Molin, DGM ;

Person, A ;

Runyan, RB ;

Gittenberger-de Groot, AC ;

McDonald, JA ;

Klewer, SE .

DEVELOPMENTAL BIOLOGY, 2002, 248 (01) :170-181

[10] Improved development of human embryonic stem cell-derived embryoid bodies by stirred vessel cultivation [J].

Cameron, C. M. ;

Hu, Wei-Shou ;

Kaufman, Dan S. .

BIOTECHNOLOGY AND BIOENGINEERING, 2006, 94 (05) :938-948

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