The Claisen rearrangement approach to fused bicyclic medium-ring oxacycles

被引：16

作者：

Burton, Jonathan W. ^{[1
,2
]}

Anderson, Edward A. ^{[1
]}

O'Sullivan, Paul T. ^{[1
]}

Collins, Ian ^{[3
]}

Davies, John E. ^{[1
]}

Bond, Andrew D. ^{[1
]}

Feeder, Neil ^{[1
]}

Holmes, Andrew B. ^{[1
,4
]}

机构：

[1] Univ Cambridge, Dept Chem, Cambridge CB2 1EW, England

[2] Univ Oxford, Chem Res Lab, Oxford OX1 3TA, England

[3] Inst Canc Res, Sutton SM2 5NG, Surrey, England

[4] Univ Melbourne, Inst Bio21, Sch Chem, Melbourne, Vic 3010, Australia

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2008年 / 6卷 / 04期

关键词：

D O I：

10.1039/b715354f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of five fused-bicyclic medium-ring lactones carrying identical ring-fusion to that in the polyether toxins is described using an enolate hydroxylation, intramolecular hydrosilation, Claisen rearrangement sequence.

引用

页码：693 / 702

页数：10

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