Chronic obstructive pulmonary disease and its comorbidities

被引:14
作者
Rabinovich, Roberto A. [1 ]
MacNee, William [1 ]
机构
[1] Univ Edinburgh, Queens Med Res Inst, UoE MRC Ctr Inflammat Res, Edinburgh EH16 4TJ, Midlothian, Scotland
关键词
BODY-MASS INDEX; SYSTEMIC INFLAMMATION; ARTERIAL STIFFNESS; LUNG-FUNCTION; CARDIOVASCULAR-DISEASE; ADVANCED COPD; MORTALITY; OSTEOPOROSIS; PREVALENCE; DEPRESSION;
D O I
10.12968/hmed.2011.72.3.137
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Systemic consequences and associated comorbidities are highly prevalent in patients with chronic obstructive pulmonary disease and have a strong impact on morbidity and mortality. This review examines their prevalence and clinical features, and discusses the pathogenic mechanisms, prognosis and implications for therapy.
引用
收藏
页码:137 / 145
页数:9
相关论文
共 76 条
[1]   Systemic effects of chronic obstructive pulmonary disease [J].
Agustí, AGN ;
Noguera, A ;
Sauleda, J ;
Sala, E ;
Pons, J ;
Busquets, X .
EUROPEAN RESPIRATORY JOURNAL, 2003, 21 (02) :347-360
[2]   Neurotransmitter, peptide and cytokine processes in relation to depressive disorder: Comorbidity between depression and neurodegenerative disorders [J].
Anisman, Hymie ;
Merali, Zul ;
Hayley, Shawn .
PROGRESS IN NEUROBIOLOGY, 2008, 85 (01) :1-74
[3]   Hospitalizations and mortality in the Lung Health Study [J].
Anthonisen, NR ;
Connett, JE ;
Enright, PL ;
Manfreda, J .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2002, 166 (03) :333-339
[4]   The effects of a smoking cessation intervention on 14.5-year mortality - A randomized clinical trial [J].
Anthonisen, NR ;
Skeans, MA ;
Wise, RA ;
Manfreda, J ;
Kanner, RE ;
Connett, JE .
ANNALS OF INTERNAL MEDICINE, 2005, 142 (04) :233-239
[5]   Pulmonary hypertension in chronic obstructive pulmonary disease [J].
Barberà, JA ;
Peinado, VI ;
Santos, S .
EUROPEAN RESPIRATORY JOURNAL, 2003, 21 (05) :892-905
[6]  
Ben-Zaken Cohen Sigal, 2007, Am J Respir Crit Care Med, V176, P113
[7]   Telomere length as an indicator of biological aging - The gender effect and relation with pulse pressure and pulse wave velocity [J].
Benetos, A ;
Okuda, K ;
Lajemi, M ;
Kimura, M ;
Thomas, F ;
Skurnick, J ;
Labat, C ;
Bean, K ;
Aviv, A .
HYPERTENSION, 2001, 37 (02) :381-385
[8]   Raised CRP levels mark metabolic and functional impairment in advanced COPD [J].
Broekhuizen, R ;
Wouters, EFM ;
Creutzberg, EC ;
Schols, AMWJ .
THORAX, 2006, 61 (01) :17-22
[9]   Administration of growth hormone to underweight patients with chronic obstructive pulmonary disease - A prospective, randomized, controlled study [J].
Burdet, L ;
deMuralt, B ;
Schutz, Y ;
Pichard, C ;
Fitting, JW .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1997, 156 (06) :1800-1806
[10]   Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease [J].
Calverley, Peter M. A. ;
Anderson, Julie A. ;
Celli, Bartolome ;
Ferguson, Gary T. ;
Jenkins, Christine ;
Jones, Paul W. ;
Yates, Julie C. ;
Vestbo, Jorgen ;
Calverley, P. M. A. ;
Anderson, J. A. ;
Celli, B. ;
Ferguson, G. T. ;
Jenkins, C. ;
Jones, P. W. ;
Knobil, K. ;
Yates, J. C. ;
Vestbo, J. ;
Cherniack, R. ;
Similowski, T. ;
Cleland, J. ;
Whitehead, A. ;
Wise, R. ;
McGarvey, L. ;
John, M. .
NEW ENGLAND JOURNAL OF MEDICINE, 2007, 356 (08) :775-789