The MOGE(S) classification for cardiomyopathies: current status and future outlook

被引:32
作者
Westphal, Julian G. [1 ]
Rigopoulos, Angelos G. [2 ,3 ]
Bakogiannis, Constantinos [4 ]
Ludwig, Sarah E. [1 ]
Mavrogeni, Sophie [5 ]
Bigalke, Boris [6 ]
Doenst, Torsten [7 ]
Pauschinger, Matthias [8 ]
Tschoepe, Carsten [9 ,10 ,11 ]
Schulze, P. Christian [1 ]
Noutsias, Michel [1 ,3 ]
机构
[1] Friedrich Schiller Univ Jena, Dept Internal Med 1, Div Cardiol Pneumol Angiol & Intens Med Care, Univ Hosp Jena, D-107747 Jena, Germany
[2] Leopoldina Hosp Schweinfurt, Dept Cardiol, Gustav Adolf Str, D-897422 Schweinfurt, Germany
[3] Martin Luther Univ Halle Wittenberg, Dept Internal Med 3, Div Cardiol Angiol & Intens Med Care, Univ Hosp Halle, Ernst Grube Str 40, D-06120 Halle, Saale, Germany
[4] Aristotle Univ Thessaloniki, Dept Cardiol 3, Ippokrateio Hosp, Konstantinoupoleos 49, Thessaloniki 54642, Greece
[5] Onassis Cardiac Surg Ctr, 50 Esperou St, Athens 17561, Greece
[6] Charite Univ Med Berlin, Dept Cardiol, CBF, D-3012200 Berlin, Germany
[7] Friedrich Schiller Univ Jena, Dept Cardiothorac Surg, Univ Hosp Jena, Jena, Germany
[8] Paracelsus Med Univ, Dept Cardiol, Internal Med 8, Nuremberg Gen Hosp, Nurnberg, Germany
[9] Charite Univ Med Berlin, Dept Cardiol, CVK, Berlin, Germany
[10] Charite Univ Med Berlin, Deutsch Zentrum Herz Kreislaufforsch DZHK Standor, CVK, Berlin, Germany
[11] BCRT, CVK, Berlin, Germany
关键词
Cardiomyopathies; Classification; MOGE(S); Genetic mutations; Myocarditis; Diagnosis; PHENOTYPE-GENOTYPE NOMENCLATURE; GIANT-CELL MYOCARDITIS; AMERICAN-HEART-ASSOCIATION; DILATED CARDIOMYOPATHY; PARVOVIRUS B19; HYPERTROPHIC CARDIOMYOPATHY; IMMUNOSUPPRESSIVE THERAPY; SCIENTIFIC STATEMENT; CLINICAL-APPLICATION; EUROPEAN-SOCIETY;
D O I
10.1007/s10741-017-9641-4
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cardiomyopathies are complex diseases of multifactorial pathogenesis and have a high morbidity and mortality. Over the past decades, several revisions of classifications and definitions of cardiomyopathies have been proposed, primarily focusing on the phenotypic characterization of cardiomyopathies. The MOGE(S) classification system published in 2013 encompasses the classification of rapidly growing knowledge on genetic mutations, acquired causes (i.e., intramyocardial inflammation, viral infections), and further conditions involved in the induction of cardiomyopathies (e.g., storage diseases, toxicity). It is based on five attributes, including morphofunctional characteristics (M), organ involvement (O), genetic or familial inheritance pattern (G), etiological annotation (E), and optional information about the heart failure functional status (S). This review summarizes the development, the cornerstones of the MOGE(S) classification, and the published data on the clinical relevance of the MOGE(S) classification. We furthermore discuss new issues which might be considered for future updates of the MOGE(S) classification of cardiomyopathies.
引用
收藏
页码:743 / 752
页数:10
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