Outbreak of Burkholderia cepacia complex infections associated with contaminated octenidine mouthwash solution, Germany, August to September 2018

被引:31
作者
Becker, Soeren L. [1 ]
Berger, Fabian K. [1 ]
Feldner, Susanne K. [2 ]
Karliova, Irem [2 ]
Haber, Manfred [3 ]
Mellmann, Alexander [4 ]
Schaefers, Hans-Joachim [2 ]
Gaertner, Barbara [1 ]
机构
[1] Saarland Univ, Inst Med Microbiol & Hyg, Homburg, Germany
[2] Saarland Univ, Dept Thorac & Cardiovasc Surg, Homburg, Germany
[3] Saarland Univ, Hosp Pharm, Homburg, Germany
[4] Univ Hosp Munster, Inst Hyg, Munster, Germany
关键词
LIQUID DOCUSATE;
D O I
10.2807/1560-7917.ES.2018.23.42.1800540
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Three German patients developed nosocomial pneumonia after cardiac surgery and had Burkholderia cepacia complex detected in respiratory specimens. Two patients died of septic multi-organ failure. Wholegenome sequencing detected genetically identical B. cepacia complex strains in patient samples, from a batch of octenidine mouthwash solution, which had been used for nursing care, as well as in samples obtained from the manufacturer during production. Contamination of medical products during manufacturing may lead to international outbreaks.
引用
收藏
页码:5 / 8
页数:4
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