Two New Alkaloids from Narcissus serotinus L.

被引:18
作者
Pigni, Natalia B. [1 ]
Berkov, Strahil [1 ]
Elamrani, Abdelaziz [2 ]
Benaissa, Mohammed [2 ]
Viladomat, Francesc [1 ]
Codina, Carles [1 ]
Bastida, Jaume [1 ]
机构
[1] Univ Barcelona, Fac Pharm, Dept Nat Prod Plant Biol & Soil Sci, Barcelona, Spain
[2] Univ Hassan 2, Dept Chem, Fac Sci Ain Chock, Casablanca, Morocco
关键词
Narcissus serotinus; Amaryllidaceae; alkaloids; narseronine; 1-O-(3 '-acetoxybutanoyl)lycorine; GALANTHUS-NIVALIS; CLIVIA-NOBILIS; AMARYLLIDACEAE;
D O I
10.3390/molecules15107083
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Amaryllidaceae family is well known for the presence of an exclusive group of alkaloids with a wide range of biological activities. Narcissus serotinus L. is a plant belonging to this family and its geographical distribution is mainly located along the Mediterranean coast. In the present work, specimens collected near Casablanca (Morocco) were used to study the alkaloid content of this species. Starting with 350 g of the whole plant we used standard extraction and purification procedures to obtain fractions and compounds for GC-MS and NMR analysis. As well as five known alkaloids, we isolated two new compounds: 1-O-(3'-acetoxybutanoyl)lycorine and narseronine. The latter has been previously published, but with an erroneous structure.
引用
收藏
页码:7083 / 7089
页数:7
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